2-(3-Bromophenyl)pyrrolidine

Base Information

Chemical Name:2-(3-Bromophenyl)pyrrolidine
CAS No.:383127-79-5
Molecular Formula:C10H12BrN
Molecular Weight:226.116
Hs Code.:2933990090
European Community (EC) Number:816-829-3
DSSTox Substance ID:DTXSID30400796
Nikkaji Number:J2.179.804E
Mol file:383127-79-5.mol

Synonyms:2-(3-bromophenyl)pyrrolidine;383127-79-5;2-(3-BROMO-PHENYL)-PYRROLIDINE;Pyrrolidine, 2-(3-bromophenyl)-;SCHEMBL2527089;DTXSID30400796;FIRVFEHVSIYTIO-UHFFFAOYSA-N;BBL020784;MFCD02663522;STK893474;AKOS000176134;AKOS016343604;SB36953;SB45396;AC-24295;BS-13639;AM20040336;BB 0249537;CS-0060393;FT-0646167;EN300-49798;A26415;I11305;Z295459704

Suppliers and Price of 2-(3-Bromophenyl)pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(3-Bromophenyl)pyrrolidine
50mg
$ 45.00

SynQuest Laboratories
2-(3-Bromophenyl)pyrrolidine 97%
1 g
$ 384.00

SynQuest Laboratories
2-(3-Bromophenyl)pyrrolidine 97%
5 g
$ 1280.00

Labseeker
2-(3-BROMO-PHENYL)-PYRROLIDINE 95
1g
$ 462.00

J&W Pharmlab
2-(3-Bromo-phenyl)-pyrrolidine 98%
5g
$ 630.00

J&W Pharmlab
2-(3-Bromo-phenyl)-pyrrolidine 98%
1g
$ 155.00

J&W Pharmlab
2-(3-Bromo-phenyl)-pyrrolidine 98%
100mg
$ 88.00

J&W Pharmlab
2-(3-Bromo-phenyl)-pyrrolidine 98%
500mg
$ 129.00

American Custom Chemicals Corporation
2-(3-BROMO-PHENYL)-PYRROLIDINE 95.00%
1G
$ 750.68

American Custom Chemicals Corporation
2-(3-BROMO-PHENYL)-PYRROLIDINE 95.00%
0.25G
$ 639.00

Total 29 raw suppliers

Chemical Property of 2-(3-Bromophenyl)pyrrolidine

Chemical Property:

Vapor Pressure:0.00269mmHg at 25°C
Refractive Index:1.566
Boiling Point:286.1 °C at 760 mmHg
PKA:9.95±0.10(Predicted)
Flash Point:126.8 °C
PSA：12.03000
Density:1.369 g/cm³
LogP:3.20240
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:225.01531
Heavy Atom Count:12
Complexity:149

Purity/Quality:

99%, ^*data from raw suppliers

2-(3-Bromophenyl)pyrrolidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(NC1)C2=CC(=CC=C2)Br

Technology Process of 2-(3-Bromophenyl)pyrrolidine

There total 4 articles about 2-(3-Bromophenyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 374589-00-1
5-(3-bromophenyl)-3,4-dihydro-2H-pyrrole

: 383127-79-5,1217632-62-6
(+/-) 2-(3-bromophenyl)pyrrolidine

Guidance literature:: 5-(3-bromophenyl)-3,4-dihydro-2H-pyrrole; With sodium tetrahydroborate; In ethanol; at 20 ℃;

With hydrogenchloride; water; In ethanol; at 0 ℃; for 0.75h; pH=1;

With sodium hydroxide; water; In ethanol;

Reference yield:

: 207681-67-2
N-methoxy-N-methyl-3-bromobenzamide

: 383127-79-5,1217632-62-6
(+/-) 2-(3-bromophenyl)pyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: Mg / tetrahydrofuran / 1 h / Heating

1.2: tetrahydrofuran / 18 h / 20 °C

1.3: 63 percent / HCl / ethanol; tetrahydrofuran / 3 h / 20 °C

2.1: NaBH₄; acetic acid / methanol / -45 °C

With sodium tetrahydroborate; magnesium; acetic acid; In tetrahydrofuran; methanol;
DOI:10.1021/jo050161r

Reference yield:

: 108-36-1
1,3-dibromobenzene

: 383127-79-5,1217632-62-6
(+/-) 2-(3-bromophenyl)pyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / diethyl ether / 0.5 h / Inert atmosphere; Reflux

1.2: -78 - 20 °C / Inert atmosphere; Reflux

2.1: sodium tetrahydroborate / ethanol / 12 h / 0 - 20 °C

With sodium tetrahydroborate; triethylamine; In diethyl ether; ethanol;
DOI:10.1021/jacs.7b03131