(2S,4S,5R,6S)-7-(4-methoxybenzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4,6-trimethylheptan-1-ol

Base Information Edit

Chemical Name:(2S,4S,5R,6S)-7-(4-methoxybenzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4,6-trimethylheptan-1-ol
CAS No.:945401-95-6
Molecular Formula:C₂₄H₄₄O₄Si
Molecular Weight:424.696
Hs Code.:
Mol file:945401-95-6.mol

Synonyms:(2S,4S,5R,6S)-7-(4-methoxybenzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4,6-trimethylheptan-1-ol

Suppliers and Price of (2S,4S,5R,6S)-7-(4-methoxybenzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4,6-trimethylheptan-1-ol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,4S,5R,6S)-7-(4-methoxybenzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4,6-trimethylheptan-1-ol Edit

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,4S,5R,6S)-7-(4-methoxybenzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4,6-trimethylheptan-1-ol

There total 2 articles about (2S,4S,5R,6S)-7-(4-methoxybenzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4,6-trimethylheptan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 945401-94-5
C₃₄H₅₅NO₅Si

: 945401-95-6
(2S,4S,5R,6S)-7-(4-methoxybenzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4,6-trimethylheptan-1-ol

Guidance literature:: With borane-ammonia complex; lithium diisopropyl amide; In tetrahydrofuran; hexane; at 0 - 20 ℃;
DOI:10.1021/jm061385k

Reference yield:

: 132969-64-3
tert-Butyl-[(1S,2S)-1-((R)-2-iodo-1-methyl-ethyl)-3-(4-methoxy-benzyloxy)-2-methyl-propoxy]-dimethyl-silane

: 945401-95-6
(2S,4S,5R,6S)-7-(4-methoxybenzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4,6-trimethylheptan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: LDA; LiCl / tetrahydrofuran; hexane / -78 - 20 °C

1.2: 6.7 g / tetrahydrofuran; hexane / 0 - 20 °C

2.1: 96 percent / LDA; BH₃*NH₃ / tetrahydrofuran; hexane / 0 - 20 °C

With borane-ammonia complex; lithium chloride; lithium diisopropyl amide; In tetrahydrofuran; hexane;
DOI:10.1021/jm061385k