2,3-methylenedioxy-9-((p-nitrophenylsulfonyl)oxy)-10-methoxyprotoberberine chloride

Base Information

• Chemical Name: 2,3-methylenedioxy-9-((p-nitrophenylsulfonyl)oxy)-10-methoxyprotoberberine chloride
• CAS No.: 1095272-04-0
• Molecular Formula: C₂₅H₁₉N₂O₈S*Cl
• Molecular Weight: 542.953

Synonyms:2,3-methylenedioxy-9-((p-nitrophenylsulfonyl)oxy)-10-methoxyprotoberberine chloride

Chemical Property of 2,3-methylenedioxy-9-((p-nitrophenylsulfonyl)oxy)-10-methoxyprotoberberine chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-methylenedioxy-9-((p-nitrophenylsulfonyl)oxy)-10-methoxyprotoberberine chloride

There total 2 articles about 2,3-methylenedioxy-9-((p-nitrophenylsulfonyl)oxy)-10-methoxyprotoberberine chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.7%

berberrubine chloride (15401-69-1) + 4-Nitrobenzenesulfonyl chloride (98-74-8) → 2,3-methylenedioxy-9-((p-nitrophenylsulfonyl)oxy)-10-methoxyprotoberberine chloride (1095272-04-0)

Guidance literature:

In chloroform; for 7h;

Reference yield:

berberine chloride (633-65-8) → 2,3-methylenedioxy-9-((p-nitrophenylsulfonyl)oxy)-10-methoxyprotoberberine chloride (1095272-04-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 195 - 210 °C / 30 - 40 Torr

2: triethylamine / acetonitrile / 70 °C

With triethylamine; In acetonitrile;

DOI:10.3390/molecules22081257

Reference yield: 33.9%

2,3-methylenedioxy-9-((p-nitrophenylsulfonyl)oxy)-10-methoxyprotoberberine chloride (1095272-04-0) → 10-methoxy-5,6,7,8,13,13a-hexahydro-2H-1,3-dioxolano[4,5-g]isoquinolino[3,2-a]isoquinolin-9-yl 4-nitrobenzenesulfonate (1095271-71-8)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 3h; Product distribution / selectivity; Heating / reflux;

upstream raw materials:

berberrubine chloride

4-Nitrobenzenesulfonyl chloride

berberine chloride

Downstream raw materials:

10-methoxy-5,6,7,8,13,13a-hexahydro-2H-1,3-dioxolano[4,5-g]isoquinolino[3,2-a]isoquinolin-9-yl 4-nitrobenzenesulfonate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1095272-04-0 2,3-methylenedioxy-9-((p-nitrophenylsulfonyl)oxy)-10-methoxyprotoberberine chloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send