C₃₀H₂₅N₄O₄S^(1-)*Na⁽¹⁺⁾

Base Information

• Chemical Name: C₃₀H₂₅N₄O₄S^(1-)*Na⁽¹⁺⁾
• CAS No.: 1261277-12-6
• Molecular Formula: C₃₀H₂₅N₄O₄S*Na
• Molecular Weight: 560.609
• Mol file: 1261277-12-6.mol

Synonyms:C₃₀H₂₅N₄O₄S^(1-)*Na⁽¹⁺⁾

Chemical Property of C₃₀H₂₅N₄O₄S^(1-)*Na⁽¹⁺⁾

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₂₅N₄O₄S^(1-)*Na⁽¹⁺⁾

There total 13 articles about C₃₀H₂₅N₄O₄S^(1-)*Na⁽¹⁺⁾ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C32H30N4O4S (1261277-10-4) → C30H25N4O4S(1-)*Na(1+) (1261277-12-6)

Guidance literature:

C₃₂H₃₀N₄O₄S; With water; sodium hydroxide; In methanol; acetonitrile; for 6h;

With hydrogenchloride; In methanol; water; acetonitrile; pH=9;

Reference yield:

4-nitro-benzoyl chloride (122-04-3) → C30H25N4O4S(1-)*Na(1+) (1261277-12-6)

Guidance literature:

Multi-step reaction with 5 steps

1.1: dmap; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 4 h / 50 °C

2.1: zinc; acetic acid / acetonitrile / 6 h

3.1: potassium carbonate; isobutyl chloroformate / tetrahydrofuran / 1 h

3.2: 72 h

4.1: 16 h / 20 °C

5.1: sodium hydroxide; water / acetonitrile; methanol / 6 h

5.2: pH 9

With dmap; water; potassium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; sodium hydroxide; zinc; isobutyl chloroformate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

1-tosyl-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one (24310-36-9) → C30H25N4O4S(1-)*Na(1+) (1261277-12-6)

Guidance literature:

Multi-step reaction with 9 steps

1.1: trichlorophosphate / 5 h / 20 °C / Reflux

1.2: Cooling with ice

2.1: ethanol; sodium / 0.5 h / Cooling with ice

2.2: 3.5 h / 0 °C / Reflux

3.1: hydrogen bromide; acetic acid / Reflux

3.2: 6 h / Reflux

4.1: thionyl chloride / 70 °C

4.2: 3 h / 760.05 Torr

5.1: dmap; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 4 h / 50 °C

6.1: zinc; acetic acid / acetonitrile / 6 h

7.1: potassium carbonate; isobutyl chloroformate / tetrahydrofuran / 1 h

7.2: 72 h

8.1: 16 h / 20 °C

9.1: sodium hydroxide; water / acetonitrile; methanol / 6 h

9.2: pH 9

With dmap; thionyl chloride; ethanol; water; hydrogen bromide; sodium; potassium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; sodium hydroxide; zinc; trichlorophosphate; isobutyl chloroformate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; acetonitrile;

upstream raw materials:

1-tosyl-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one

methyl N-tosylanthranilate

4-nitro-benzoyl chloride

ethyl 6-(4-nitrobenzoyl)-5,6-dihydro-4H-benzo[b]thieno[2,3-d]azepine-2-carboxylate

Downstream raw materials:

C₃₅H₃₁N₅O₃S₂