1-(4-Nitrobenzyl)-4-(propylsulfonyl)piperazine

Base Information

Chemical Name:1-(4-Nitrobenzyl)-4-(propylsulfonyl)piperazine
CAS No.:428830-45-9
Molecular Formula:C₁₄H₂₁N₃O₄S
Molecular Weight:327.404
Hs Code.:
European Community (EC) Number:684-548-1
ChEMBL ID:CHEMBL1623246

Synonyms:1-(4-nitrobenzyl)-4-(propylsulfonyl)piperazine;1-[(4-nitrophenyl)methyl]-4-propylsulfonylpiperazine;428830-45-9;Oprea1_428702;Oprea1_567738;SCHEMBL3446990;CHEMBL1623246;UWWULTFASUQHHK-UHFFFAOYSA-N;STK147208;AKOS000552099

Suppliers and Price of 1-(4-Nitrobenzyl)-4-(propylsulfonyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-(4-Nitrobenzyl)-4-(propylsulfonyl)piperazine

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:327.12527733
Heavy Atom Count:22
Complexity:456

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCS(=O)(=O)N1CCN(CC1)CC2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of 1-(4-Nitrobenzyl)-4-(propylsulfonyl)piperazine

There total 3 articles about 1-(4-Nitrobenzyl)-4-(propylsulfonyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 100-11-8
1-bromomethyl-4-nitro-benzene

: 505068-18-8
1-(propylsulfonyl)piperazine

: 428830-45-9
1-nitrobenzyl-4-propylsulfonyl piperazine

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 1.16667h;

Reference yield:

: 913952-86-0
tert-butyl 4-(propylsulfonyl)piperazine-1-carboxylate

: 428830-45-9
1-nitrobenzyl-4-propylsulfonyl piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / methanol; water / 3 h / 60 °C

2: N,N-dimethyl-formamide; potassium carbonate / 20 °C

With hydrogenchloride; potassium carbonate; N,N-dimethyl-formamide; In methanol; water;

Reference yield:

: 1132825-82-1
4-(propane-1-sulfonyl)-piperazine-1-carboxylic acid ethyl ester

: 428830-45-9
1-nitrobenzyl-4-propylsulfonyl piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol; water / 20 h / 100 °C

2: potassium carbonate / N,N-dimethyl-formamide / 1.17 h / 0 - 20 °C

With sodium hydroxide; potassium carbonate; In ethanol; water; N,N-dimethyl-formamide;