tert-butyl N-methyl-N-[(4-methylbenzenesulfonyl)oxy]carbamate

Base Information

Chemical Name:tert-butyl N-methyl-N-[(4-methylbenzenesulfonyl)oxy]carbamate
CAS No.:25370-96-1
Molecular Formula:C₁₃H₁₉NO₅S
Molecular Weight:301.364
Hs Code.:
European Community (EC) Number:843-541-5

Synonyms:tert-butyl N-methyl-N-[(4-methylbenzenesulfonyl)oxy]carbamate;25370-96-1;[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino] 4-methylbenzenesulfonate;EN300-218054;tert-butylN-methyl-N-[(4-methylbenzenesulfonyl)oxy]carbamate

Suppliers and Price of tert-butyl N-methyl-N-[(4-methylbenzenesulfonyl)oxy]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of tert-butyl N-methyl-N-[(4-methylbenzenesulfonyl)oxy]carbamate

Chemical Property:

Melting Point:69-72 °C(Solv: ligroine (8032-32-4))
Boiling Point:377.1±35.0 °C(Predicted)
Density:1.219±0.06 g/cm3(Predicted)
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:301.09839388
Heavy Atom Count:20
Complexity:427

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)ON(C)C(=O)OC(C)(C)C

Technology Process of tert-butyl N-methyl-N-[(4-methylbenzenesulfonyl)oxy]carbamate

There total 2 articles about tert-butyl N-methyl-N-[(4-methylbenzenesulfonyl)oxy]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.8%

: 24424-99-5
di-tert-butyl dicarbonate

: 4229-44-1
N-methylhydroxyamine hydrochloride

: 98-59-9
p-toluenesulfonyl chloride

: 25370-96-1
O-(p-toluenesulfonyl)-N-tert-butoxycarbonyl-N-methylhydroxylamine

Guidance literature:: di-tert-butyl dicarbonate; N-methylhydroxyamine hydrochloride; With potassium carbonate; In tetrahydrofuran; water; at 0 - 20 ℃; for 5h; Inert atmosphere; Cooling with ice;

p-toluenesulfonyl chloride; With triethylamine; In dichloromethane; at 20 ℃; for 18h; Inert atmosphere;
DOI:10.1039/d0ob02122a

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 25370-96-1
O-(p-toluenesulfonyl)-N-tert-butoxycarbonyl-N-methylhydroxylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / potassium carbonate / tetrahydrofuran; H₂O / 5 h / 0 - 20 °C

2: 76 percent / triethylamine / CH₂Cl₂ / 18 h / 20 °C

With potassium carbonate; triethylamine; In tetrahydrofuran; dichloromethane; water;
DOI:10.1021/ol701774y