bis<2-(1-phenyl-3-pentafluoroethyl-4-trifluoromethylpyrazol-5-ylamino)ethyl> disulfide

Base Information

• Chemical Name: bis<2-(1-phenyl-3-pentafluoroethyl-4-trifluoromethylpyrazol-5-ylamino)ethyl> disulfide
• CAS No.: 132631-94-8
• Molecular Formula: C₂₈H₂₀F₁₆N₆S₂
• Molecular Weight: 808.613
• Mol file: 132631-94-8.mol

Synonyms:bis<2-(1-phenyl-3-pentafluoroethyl-4-trifluoromethylpyrazol-5-ylamino)ethyl> disulfide

Chemical Property of bis<2-(1-phenyl-3-pentafluoroethyl-4-trifluoromethylpyrazol-5-ylamino)ethyl> disulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis<2-(1-phenyl-3-pentafluoroethyl-4-trifluoromethylpyrazol-5-ylamino)ethyl> disulfide

There total 6 articles about bis<2-(1-phenyl-3-pentafluoroethyl-4-trifluoromethylpyrazol-5-ylamino)ethyl> disulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

cystamine hydrochloride (1072-22-6) + 1-phenyl-3-pentafluoroethyl-4-trifluoromethyl-5-fluoropyrazole (121807-33-8) → bis<2-(1-phenyl-3-pentafluoroethyl-4-trifluoromethylpyrazol-5-ylamino)ethyl> disulfide (132631-94-8)

Guidance literature:

With triethylamine; In 1,2-dimethoxyethane; at 20 ℃; for 12h;

DOI:10.1007/BF00958848

Reference yield:

phenylhydrazine (100-63-0) → bis<2-(1-phenyl-3-pentafluoroethyl-4-trifluoromethylpyrazol-5-ylamino)ethyl> disulfide (132631-94-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / Et₃N / acetonitrile / 1 h / 20 °C

2: 61 percent / Et₃N / 1,2-dimethoxy-ethane / 12 h / 20 °C

With triethylamine; In 1,2-dimethoxyethane; acetonitrile;

DOI:10.1007/BF00958848

Reference yield:

2-(Trifluoromethyl)-1,1,1,4,4,5,5,5-octafluoropentan-3-one (61637-91-0) → bis<2-(1-phenyl-3-pentafluoroethyl-4-trifluoromethylpyrazol-5-ylamino)ethyl> disulfide (132631-94-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 58 percent / Et₃N / diethyl ether / 12 h / 20 °C

2: 61 percent / Et₃N / 1,2-dimethoxy-ethane / 12 h / 20 °C

With triethylamine; In 1,2-dimethoxyethane; diethyl ether;

DOI:10.1007/BF00958848

upstream raw materials:

cystamine hydrochloride

1-phenyl-3-pentafluoroethyl-4-trifluoromethyl-5-fluoropyrazole

perfluoro-2-methylpent-2-ene

2-(Trifluoromethyl)-1,1,1,4,4,5,5,5-octafluoropentan-3-one