4,6,10-Trioxa-5-phosphahexacosanoicacid, 2-amino-5-hydroxy-11-oxo-8-[(1-oxohexadecyl)oxy]-, 5-oxide

Base Information

• Chemical Name: 4,6,10-Trioxa-5-phosphahexacosanoicacid, 2-amino-5-hydroxy-11-oxo-8-[(1-oxohexadecyl)oxy]-, 5-oxide
• CAS No.: 40290-43-5
• Molecular Formula: C₃₈H₇₄NO₁₀P
• Molecular Weight: 735.98
• Mol file: 40290-43-5.mol

Synonyms:DL-Serine,2,3-bis[(1-oxohexadecyl)oxy]propyl hydrogen phosphate(ester); Serine, 2,3-bis[(1-oxohexadecyl)oxy]propylhydrogen phosphate (ester) (9CI); DL-Dipalmitoylphosphatidylserine

Chemical Property of 4,6,10-Trioxa-5-phosphahexacosanoicacid, 2-amino-5-hydroxy-11-oxo-8-[(1-oxohexadecyl)oxy]-, 5-oxide

Chemical Property:

• Boiling Point: 782.6°Cat760mmHg
• Flash Point: 427.1°C
• Density: 1.057g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,6,10-Trioxa-5-phosphahexacosanoicacid, 2-amino-5-hydroxy-11-oxo-8-[(1-oxohexadecyl)oxy]-, 5-oxide

There total 13 articles about 4,6,10-Trioxa-5-phosphahexacosanoicacid, 2-amino-5-hydroxy-11-oxo-8-[(1-oxohexadecyl)oxy]-, 5-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

O-benzyl O-[(S)-2-(benzyloxycarbonyl)-2-(benzyloxycarbonylamino)ethyl] O-[1,2-di-(O-palmitoyl)-sn-glycer-3-yl] phosphate (1240407-85-5) → dipalmitoylphosphatidyl-L-serine (3036-82-6,40290-42-4,40290-43-5,72904-02-0)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In acetic acid; at 20 ℃; for 48h;

DOI:10.1007/s00726-009-0447-0

Reference yield: 85.0%

1,2-dipalmitoyl-sn-glycerol-3-phosphoryl-N-Troc-serine → dipalmitoylphosphatidyl-L-serine (3036-82-6,40290-42-4,40290-43-5,72904-02-0)

Guidance literature:

With acetic acid; zinc; at 25 ℃; for 7h;

Reference yield:

O-(1,2-O-dipalmitoyl-sn-3-glyceryl) O- O-phenyl phosphate → dipalmitoylphosphatidyl-L-serine (3036-82-6,40290-42-4,40290-43-5,72904-02-0)

Guidance literature:

With hydrogen; platinum(IV) oxide;

upstream raw materials:

1,2-di-O-hexacecanoyl-3-O-benzyl-sn-glycerol

1,2-dipalmitoyl-sn-glycerol

1-hexadecylcarboxylic acid

O-benzyl O-[(S)-2-(benzyloxycarbonyl)-2-(benzyloxycarbonylamino)ethyl] O-[1,2-di-(O-palmitoyl)-sn-glycer-3-yl] phosphate

Downstream raw materials:

1,2-dipalmitoyl-sn-glycero-3-phosphatidic acid

C₃₇H₇₁O₁₁P

C₃₇H₇₁O₁₀P

C₃₇H₇₂NO₉P

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