[2(1S,3E),2S]-2-[[1-tert-butyl-4-(trimethylsilanyl)but-3-enyl]amino]-2-phenylethanol

Base Information

Chemical Name:[2(1S,3E),2S]-2-[[1-tert-butyl-4-(trimethylsilanyl)but-3-enyl]amino]-2-phenylethanol
CAS No.:408351-32-6
Molecular Formula:C₁₉H₃₃NOSi
Molecular Weight:319.563
Hs Code.:

Synonyms:[2(1S,3E),2S]-2-[[1-tert-butyl-4-(trimethylsilanyl)but-3-enyl]amino]-2-phenylethanol

Suppliers and Price of [2(1S,3E),2S]-2-[[1-tert-butyl-4-(trimethylsilanyl)but-3-enyl]amino]-2-phenylethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [2(1S,3E),2S]-2-[[1-tert-butyl-4-(trimethylsilanyl)but-3-enyl]amino]-2-phenylethanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [2(1S,3E),2S]-2-[[1-tert-butyl-4-(trimethylsilanyl)but-3-enyl]amino]-2-phenylethanol

There total 3 articles about [2(1S,3E),2S]-2-[[1-tert-butyl-4-(trimethylsilanyl)but-3-enyl]amino]-2-phenylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 762-72-1
allyl-trimethyl-silane

: 408351-24-6
(4S)-2-tert-butyl-4-phenyl-1,3-oxazolidine

: 408351-32-6
[2(1S,3E),2S]-2-[[1-tert-butyl-4-(trimethylsilanyl)but-3-enyl]amino]-2-phenylethanol

: [2(1R,3E),2S]-2-[[1-tert-butyl-4-(trimethylsilanyl)but-3-enyl]amino]-2-phenylethanol

Guidance literature:: allyl-trimethyl-silane; With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; cyclohexane; at -78 - 20 ℃; for 0.5h;

(4S)-2-tert-butyl-4-phenyl-1,3-oxazolidine; In tetrahydrofuran; cyclohexane; at -78 - 0 ℃; for 1.33333h;
DOI:10.1021/jo010779a

Reference yield:

: 20989-17-7
(2S)-2-phenylglycinol

: 408351-32-6
[2(1S,3E),2S]-2-[[1-tert-butyl-4-(trimethylsilanyl)but-3-enyl]amino]-2-phenylethanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: MgSO₄ / tetrahydrofuran / 2 h / 20 °C

2.1: sec-butyllithium; N,N,N',N'-tetramethylethylenediamine / tetrahydrofuran; cyclohexane / 0.5 h / -78 - 20 °C

2.2: 80 percent / tetrahydrofuran; cyclohexane / 1.33 h / -78 - 0 °C

With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; magnesium sulfate; In tetrahydrofuran; cyclohexane;
DOI:10.1021/jo010779a

Reference yield:

: 630-19-3
pivalaldehyde

: 408351-32-6
[2(1S,3E),2S]-2-[[1-tert-butyl-4-(trimethylsilanyl)but-3-enyl]amino]-2-phenylethanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: MgSO₄ / tetrahydrofuran / 2 h / 20 °C

2.1: sec-butyllithium; N,N,N',N'-tetramethylethylenediamine / tetrahydrofuran; cyclohexane / 0.5 h / -78 - 20 °C

2.2: 80 percent / tetrahydrofuran; cyclohexane / 1.33 h / -78 - 0 °C

With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; magnesium sulfate; In tetrahydrofuran; cyclohexane;
DOI:10.1021/jo010779a