4-Chloro-2-methyl-5-(1-methylhydrazino)-2,3-dihydropyridazin-3-one

Base Information

• Chemical Name: 4-Chloro-2-methyl-5-(1-methylhydrazino)-2,3-dihydropyridazin-3-one
• CAS No.: 96017-23-1
• Molecular Formula: C6H9 Cl N4 O
• Molecular Weight: 188.61
• Hs Code.: 2933990090
• European Community (EC) Number: 859-276-3
• DSSTox Substance ID: DTXSID30379175
• Nikkaji Number: J308.021H
• Wikidata: Q82168868
• Mol file: 96017-23-1.mol

Synonyms:96017-23-1;4-Chloro-2-methyl-5-(1-methylhydrazino)-2,3-dihydropyridazin-3-one;4-chloro-2-methyl-5-(1-methylhydrazin-1-yl)-2,3-dihydropyridazin-3-one;5-[amino(methyl)amino]-4-chloro-2-methylpyridazin-3-one;4-Chloro-2-methyl-5-(1-methylhydrazinyl)pyridazin-3(2H)-one;94415-35-7;4-chloro-2-methyl-5-(1-methylhydrazino)-3(2h)-pyridazinone;4-Chloro-2-methyl-5-(1-methylhydrazino)pyridazin-3(2H)-one;SCHEMBL6484911;DTXSID30379175;MFCD00052906;AKOS006229615;PS-10945;CS-0250392;FT-0618027;EN300-50650;J-514964;1-methyl-4-(1-methylhydrazino)-5-chloro-6-pyridazone;3(2H)-Pyridazinone,4-chloro-2-methyl-5-(1-methylhydrazinyl)-

Chemical Property of 4-Chloro-2-methyl-5-(1-methylhydrazino)-2,3-dihydropyridazin-3-one

Chemical Property:

• Vapor Pressure: 0.0203mmHg at 25°C
• Melting Point: 131 °C
• Refractive Index: 1.627
• Boiling Point: 251.6°Cat760mmHg
• PKA: 3.86±0.20(Predicted)
• Flash Point: 106°C
• PSA: 64.15000
• Density: 1.46g/cm³
• LogP: 0.44390
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 188.0464886
• Heavy Atom Count: 12
• Complexity: 273

Purity/Quality:

99%, ^*data from raw suppliers

4-Chloro-2-methyl-5-(1-methylhydrazino)-2,3-dihydropyridazin-3-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.; R36/37/38:Irritating to eyes, respiratory system
• Hazard Codes: Xn:Harmful
• Statements: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.; R36/37/38:Irritating to eyes, respiratory system
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1C(=O)C(=C(C=N1)N(C)N)Cl

Technology Process of 4-Chloro-2-methyl-5-(1-methylhydrazino)-2,3-dihydropyridazin-3-one

There total 3 articles about 4-Chloro-2-methyl-5-(1-methylhydrazino)-2,3-dihydropyridazin-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

4,5-dichloro-2-methyl-3(2H)-pyridazinone (933-76-6) + methylhydrazine (60-34-4) → 4-Chloro-2-methyl-5-(1-methylhydrazino)-3-(2H)-pyridazinone (96017-23-1)

Guidance literature:

In methanol; for 10h; Ambient temperature;

DOI:10.1002/jhet.5570210501

Reference yield: 38.0%

4-Chloro-5-(1-methylhydrazino)-3(2H)-pyridazinone (96017-24-2) + dimethyl sulfate (77-78-1) → 4-Chloro-2-methyl-5-(1-methylhydrazino)-3-(2H)-pyridazinone (96017-23-1)

Guidance literature:

With sodium; In methanol; at 35 - 40 ℃; for 14h;

DOI:10.1007/s11167-005-0207-1

Reference yield:

5-(1-methylhydrazino)-3,4-dichloropyridazine → 4-Chloro-2-methyl-5-(1-methylhydrazino)-3-(2H)-pyridazinone (96017-23-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 10 percent / AcOH / 12 h / 60 °C

2: 38 percent / Na / methanol / 14 h / 35 - 40 °C

With sodium; acetic acid; In methanol;

DOI:10.1007/s11167-005-0207-1

upstream raw materials:

4,5-dichloro-2-methyl-3(2H)-pyridazinone

methylhydrazine

4-Chloro-5-(1-methylhydrazino)-3(2H)-pyridazinone

dimethyl sulfate

Downstream raw materials:

3-Benzylsulfanyl-1,6-dimethyl-1H,6H-pyridazino[4,5-e][1,3,4]thiadiazin-5-one

4-Chloro-5-{N'-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-N-methyl-hydrazino}-2-methyl-2H-pyridazin-3-one

5-(4-benzyl-1-methylthiosemicarbazido)-4-chloro-2-methyl-3(2H)-pyridazinone

4-Chloro-5-{N'-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-N-methyl-hydrazino}-2-methyl-2H-pyridazin-3-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 96017-23-1 4-CHLORO-2-METHYL-5-(1-METHYLHYDRAZINO)-2,3-DIHYDROPYRIDAZIN-3-ONE

Send

Send

Metric Ton KG G Pound L ML

Send

Send