ethylene diamine di(o-hydroxyphenylacetic acid)

Base Information

• Chemical Name: ethylene diamine di(o-hydroxyphenylacetic acid)
• CAS No.: 94770-71-5
• Molecular Formula: C₁₈H₂₀N₂O₆
• Molecular Weight: 360.367
• Mol file: 94770-71-5.mol

Synonyms:ethylene diamine di(o-hydroxyphenylacetic acid)

Chemical Property of ethylene diamine di(o-hydroxyphenylacetic acid)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethylene diamine di(o-hydroxyphenylacetic acid)

There total 3 articles about ethylene diamine di(o-hydroxyphenylacetic acid) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

ethylenediamine (107-15-3,85404-18-8) + Glyoxilic acid (298-12-4) + phenol (108-95-2,27073-41-2) → ethylenediamine-N,N'-bis(2-hydroxyphenylacetic acid) (1170-02-1) + ethylene diamine di(o-hydroxyphenylacetic acid) (94770-71-5) + ethylenediamine-N-(o-hydroxyphenylacetic)-N'-(p-hydroxyphenylacetic) acid

Guidance literature:

With sodium hydroxide; at 70 - 75 ℃; for 3h;

DOI:10.1021/jf0605749

Reference yield:

2,2'-bis-(4-hydroxy-phenyl)-2,2'-ethanediyldiamino-di-acetonitrile (98691-12-4) → ethylene diamine di(o-hydroxyphenylacetic acid) (94770-71-5)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/jo01094a021

Reference yield:

4-((2-(4hydroxybenzylideneamino)ethylimino)methyl)phenol (5340-13-6) → ethylene diamine di(o-hydroxyphenylacetic acid) (94770-71-5)

Guidance literature:

Multi-step reaction with 2 steps

2: aqueous HCl

With hydrogenchloride;

DOI:10.1021/jo01094a021

upstream raw materials:

2,2'-bis-(4-hydroxy-phenyl)-2,2'-ethanediyldiamino-di-acetonitrile

ethylenediamine

Glyoxilic acid

phenol

Refernces