4-(3-Bromophenyl)-2-methyl-1,3-thiazole

Base Information

• Chemical Name: 4-(3-Bromophenyl)-2-methyl-1,3-thiazole
• CAS No.: 342405-21-4
• Molecular Formula: C₁₀H₈BrNS
• Molecular Weight: 254.15
• Hs Code.: 2934100090
• DSSTox Substance ID: DTXSID10380128
• Wikidata: Q82170198
• Mol file: 342405-21-4.mol

Synonyms:4-(3-bromophenyl)-2-methyl-1,3-thiazole;342405-21-4;4-(3-Bromophenyl)-2-methylthiazole;VANADIUMIODIDE;SCHEMBL4821852;DTXSID10380128;MFCD02681947;AKOS003104276;PS-11554;CS-0451429;FT-0616578;EN300-79250;J-513364;4-(3-bromophenyl)-2-methyl-1,3-thiazole, AldrichCPR;F2158-1139

Chemical Property of 4-(3-Bromophenyl)-2-methyl-1,3-thiazole

Chemical Property:

• Vapor Pressure: 0.000245mmHg at 25°C
• Melting Point: 63-65
• Boiling Point: 334.6°Cat760mmHg
• Flash Point: 156.2°C
• PSA: 41.13000
• Density: 1.496g/cm³
• LogP: 3.88100
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 252.95608
• Heavy Atom Count: 13
• Complexity: 176

Purity/Quality:

98%Min ^*data from raw suppliers

4-(3-Bromophenyl)-2-methylthiazole ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=NC(=CS1)C2=CC(=CC=C2)Br

Technology Process of 4-(3-Bromophenyl)-2-methyl-1,3-thiazole

There total 1 articles about 4-(3-Bromophenyl)-2-methyl-1,3-thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

thioacetamide (62-55-5) + 2,3'-dibromoacetophenone (18523-22-3) → 4-(3-bromophenyl)-2-methyl-1,3-thiazole (342405-21-4)

Guidance literature:

In ethanol; at 80 ℃; for 0.25h; Microwave irradiation;

DOI:10.1080/10426500802715163

upstream raw materials:

thioacetamide

2,3'-dibromoacetophenone

Refernces