(1S,6R)-6-((tert-butoxycarbonyl)amino)-2,2-difluorocyclohexyl trifluoromethanesulfonate

Base Information

Chemical Name:(1S,6R)-6-((tert-butoxycarbonyl)amino)-2,2-difluorocyclohexyl trifluoromethanesulfonate
CAS No.:1207557-06-9
Molecular Formula:C₁₂H₁₈F₅NO₅S
Molecular Weight:383.337
Hs Code.:

Synonyms:(1S,6R)-6-((tert-butoxycarbonyl)amino)-2,2-difluorocyclohexyl trifluoromethanesulfonate

Suppliers and Price of (1S,6R)-6-((tert-butoxycarbonyl)amino)-2,2-difluorocyclohexyl trifluoromethanesulfonate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1S,6R)-6-((tert-butoxycarbonyl)amino)-2,2-difluorocyclohexyl trifluoromethanesulfonate

Chemical Property:

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Technology Process of (1S,6R)-6-((tert-butoxycarbonyl)amino)-2,2-difluorocyclohexyl trifluoromethanesulfonate

There total 8 articles about (1S,6R)-6-((tert-butoxycarbonyl)amino)-2,2-difluorocyclohexyl trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 358-23-6
trifluoromethylsulfonic anhydride

: 1109284-41-4
tert-butyl N-[(1R,2S)-3,3-difluoro-2-hydroxycyclohexyl]carbamate

: 1207557-06-9
(1S,6R)-6-((tert-butoxycarbonyl)amino)-2,2-difluorocyclohexyl trifluoromethanesulfonate

Guidance literature:: With pyridine; In dichloromethane; at 0 ℃; for 2h; Inert atmosphere;

Reference yield:

: 1109284-40-3
(1S,6R)-6-amino-2,2-difluorocyclohexan-1-ol

: 1207557-06-9
(1S,6R)-6-((tert-butoxycarbonyl)amino)-2,2-difluorocyclohexyl trifluoromethanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran

2: pyridine / dichloromethane / 0.25 h / Cooling with ice

With pyridine; triethylamine; In tetrahydrofuran; dichloromethane;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1207557-06-9
(1S,6R)-6-((tert-butoxycarbonyl)amino)-2,2-difluorocyclohexyl trifluoromethanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran

2: pyridine / dichloromethane / 0.25 h / Cooling with ice

With pyridine; triethylamine; In tetrahydrofuran; dichloromethane;