5-(2-([1,1'-biphenyl]-4-yl)propan-2-yl)-2,2-dimethyl-1,3-dioxane-4,6-dione

Base Information

• Chemical Name: 5-(2-([1,1'-biphenyl]-4-yl)propan-2-yl)-2,2-dimethyl-1,3-dioxane-4,6-dione
• CAS No.: 1190929-69-1
• Molecular Formula: C₂₁H₂₂O₄
• Molecular Weight: 338.403
• Mol file: 1190929-69-1.mol

Synonyms:5-(2-([1,1'-biphenyl]-4-yl)propan-2-yl)-2,2-dimethyl-1,3-dioxane-4,6-dione

Chemical Property of 5-(2-([1,1'-biphenyl]-4-yl)propan-2-yl)-2,2-dimethyl-1,3-dioxane-4,6-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(2-([1,1'-biphenyl]-4-yl)propan-2-yl)-2,2-dimethyl-1,3-dioxane-4,6-dione

There total 1 articles about 5-(2-([1,1'-biphenyl]-4-yl)propan-2-yl)-2,2-dimethyl-1,3-dioxane-4,6-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

2,2-dimethyl-5-[1-(4-phenylphenyl)ethylidene]-1,3-dioxane-4,6-dione + methylmagnesium bromide (75-16-1) → 5-(2-([1,1'-biphenyl]-4-yl)propan-2-yl)-2,2-dimethyl-1,3-dioxane-4,6-dione (1190929-69-1)

Guidance literature:

In tetrahydrofuran; diethyl ether; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/ja9076815

Reference yield: 80.0%

5-(2-([1,1'-biphenyl]-4-yl)propan-2-yl)-2,2-dimethyl-1,3-dioxane-4,6-dione (1190929-69-1) → cycl-isopropylidene malonate (2033-24-1) + 4-isopropylbiphenyl (7116-95-2)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 24h; under 760.051 Torr;

DOI:10.1002/adsc.201600535

Reference yield: 71.0%

5-(2-([1,1'-biphenyl]-4-yl)propan-2-yl)-2,2-dimethyl-1,3-dioxane-4,6-dione (1190929-69-1) → 4-isopropylbiphenyl (7116-95-2)

Guidance literature:

With methanol; palladium 10% on activated carbon; hydrogen; at 20 ℃; for 24h; under 760.051 Torr; Inert atmosphere;

DOI:10.1021/ja9076815

upstream raw materials:

methylmagnesium bromide

Downstream raw materials:

4-isopropylbiphenyl

cycl-isopropylidene malonate

2,2,5-trimethyl-1,3-dioxane-4,6-dione

5-(4-fluorobenzyl)-2,2-dimethyl-[1,3]dioxane-4,6-dione