4-methoxy-2-(methylthio)-6-(3-(pyrimidin-2-yl)phenylamino)pyrimidine-5-carbonitrile

Base Information

Chemical Name:4-methoxy-2-(methylthio)-6-(3-(pyrimidin-2-yl)phenylamino)pyrimidine-5-carbonitrile
CAS No.:1374157-68-2
Molecular Formula:C₁₇H₁₄N₆OS
Molecular Weight:350.404
Hs Code.:

Synonyms:4-methoxy-2-(methylthio)-6-(3-(pyrimidin-2-yl)phenylamino)pyrimidine-5-carbonitrile

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Chemical Property of 4-methoxy-2-(methylthio)-6-(3-(pyrimidin-2-yl)phenylamino)pyrimidine-5-carbonitrile

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Technology Process of 4-methoxy-2-(methylthio)-6-(3-(pyrimidin-2-yl)phenylamino)pyrimidine-5-carbonitrile

There total 3 articles about 4-methoxy-2-(methylthio)-6-(3-(pyrimidin-2-yl)phenylamino)pyrimidine-5-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1374157-66-0
4-chloro-2-(methylthio)-6-(3-(pyrimidin-2-yl)phenylamino)pyrimidine-5-carbonitrile

: 1374157-68-2
4-methoxy-2-(methylthio)-6-(3-(pyrimidin-2-yl)phenylamino)pyrimidine-5-carbonitrile

Guidance literature:: With methanol; potassium carbonate; at 20 - 60 ℃; for 2.5h;

Reference yield:

: 33097-13-1
4,6-dichloro-2-(methylthio)-5-pyrimidinecarbonitrile

: 1374157-68-2
4-methoxy-2-(methylthio)-6-(3-(pyrimidin-2-yl)phenylamino)pyrimidine-5-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 3 h / 20 °C

2: potassium carbonate; methanol / 2.5 h / 20 - 60 °C

With methanol; potassium carbonate; In N,N-dimethyl-formamide;

Reference yield:

: 69491-56-1
3-(pyrimidin-2-yl)aniline

: 1374157-68-2
4-methoxy-2-(methylthio)-6-(3-(pyrimidin-2-yl)phenylamino)pyrimidine-5-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 3 h / 20 °C

2: potassium carbonate; methanol / 2.5 h / 20 - 60 °C

With methanol; potassium carbonate; In N,N-dimethyl-formamide;