2,4-Dichloro-1-(2,2-diethoxyethoxy)benzene

Base Information

• Chemical Name: 2,4-Dichloro-1-(2,2-diethoxyethoxy)benzene
• CAS No.: 78830-79-2
• Molecular Formula: C12H16 Cl2 O3
• Molecular Weight: 279.163
• European Community (EC) Number: 636-061-0
• DSSTox Substance ID: DTXSID00381902
• Wikidata: Q82173080
• Mol file: 78830-79-2.mol

Synonyms:2,4-dichloro-1-(2,2-diethoxyethoxy)benzene;78830-79-2;Benzene,2,4-dichloro-1-(2,2-diethoxyethoxy)-;SCHEMBL11514164;DTXSID00381902;AKOS009159423;FT-0609997

Chemical Property of 2,4-Dichloro-1-(2,2-diethoxyethoxy)benzene

Chemical Property:

• Vapor Pressure: 8.65E-05mmHg at 25°C
• Boiling Point: 350.8°C at 760 mmHg
• Flash Point: 122.9°C
• PSA: 27.69000
• Density: 1.198g/cm³
• LogP: 3.77130
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 278.0476498
• Heavy Atom Count: 17
• Complexity: 198

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(2,4-DICHLOROPHENOXY)ACETALDEHYDE DIETHYLACETAL Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(COC1=C(C=C(C=C1)Cl)Cl)OCC

Technology Process of 2,4-Dichloro-1-(2,2-diethoxyethoxy)benzene

There total 2 articles about 2,4-Dichloro-1-(2,2-diethoxyethoxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

Bromoacetaldehyde diethyl acetal (2032-35-1) + 2,4-dichlorophenol (120-83-2,40477-79-0) → (2,4-dichlorophenoxy)acetaldehyde diethyl acetal (78830-79-2)

Guidance literature:

With potassium hydroxide; In N,N-dimethyl acetamide; at 20 ℃; Heating;

DOI:10.1016/j.tet.2015.05.029

Reference yield:

2,4-dichlorophenol (120-83-2,40477-79-0) + chloroacetaldehyde diethyl acetal (621-62-5) → (2,4-dichlorophenoxy)acetaldehyde diethyl acetal (78830-79-2)

Guidance literature:

With ethanol; sodium ethanolate;

Reference yield: 80.0%

(2,4-dichlorophenoxy)acetaldehyde diethyl acetal (78830-79-2) → (2,4-dichlorophenoxy)acetaldehyde (17944-27-3)

Guidance literature:

With sulfuric acid;

DOI:10.1021/jm00381a014

upstream raw materials:

2,4-dichlorophenol

chloroacetaldehyde diethyl acetal

Bromoacetaldehyde diethyl acetal

Downstream raw materials:

2-(2,4-dichlorophenoxymethyl)-4-methacryloyloxymethyl-1,3-dioxolane

(2,4-dichlorophenoxy)acetaldehyde

4-(2,4-dichloro-phenoxy)-trans-crotonic acid

(2,4-dichloro-phenoxy)-acetaldehyde-semicarbazone

Refernces

• 1、 Kamogawa, Hiroyoshi,Haramoto, Yuichiro,Nakazawa, Terumi,Sugiura, Harumitsu,Nanasawa, Masato. "1,3-Dioxolane Bearing Perfume and Herbicide Aldehyde Residues". . p. 1577 - 1578. Retrieved 2007/10/02.