2-(2-(benzylsulfonyl)-4-(6-methylpyridin-2-yl)-1H-imidazol-1-yl)ethanol

Base Information

Chemical Name:2-(2-(benzylsulfonyl)-4-(6-methylpyridin-2-yl)-1H-imidazol-1-yl)ethanol
CAS No.:1418306-05-4
Molecular Formula:C₁₈H₁₉N₃O₃S
Molecular Weight:357.433
Hs Code.:

Synonyms:2-(2-(benzylsulfonyl)-4-(6-methylpyridin-2-yl)-1H-imidazol-1-yl)ethanol

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Chemical Property of 2-(2-(benzylsulfonyl)-4-(6-methylpyridin-2-yl)-1H-imidazol-1-yl)ethanol

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Technology Process of 2-(2-(benzylsulfonyl)-4-(6-methylpyridin-2-yl)-1H-imidazol-1-yl)ethanol

There total 6 articles about 2-(2-(benzylsulfonyl)-4-(6-methylpyridin-2-yl)-1H-imidazol-1-yl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 1418306-02-1
2-(2-(benzylsulfonyl)-1H-imidazol-4-yl)-6-methylpyridine

: 540-51-2
2-bromoethanol

: 1418306-05-4
2-(2-(benzylsulfonyl)-4-(6-methylpyridin-2-yl)-1H-imidazol-1-yl)ethanol

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 4h;

Reference yield:

: 100-39-0
benzyl bromide

: 1418306-05-4
2-(2-(benzylsulfonyl)-4-(6-methylpyridin-2-yl)-1H-imidazol-1-yl)ethanol

Guidance literature:: Multi-step reaction with 4 steps

1: isopropyl alcohol / 1 h / 85 °C

2: sodium carbonate / N,N-dimethyl-formamide / 16 h / 50 °C

3: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1 h / 0 °C

4: caesium carbonate / N,N-dimethyl-formamide / 4 h / 80 °C

With sodium carbonate; caesium carbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; N,N-dimethyl-formamide; isopropyl alcohol;

Reference yield:

: 6940-57-4
2-acetyl-6-methylpyridine

: 1418306-05-4
2-(2-(benzylsulfonyl)-4-(6-methylpyridin-2-yl)-1H-imidazol-1-yl)ethanol

Guidance literature:: Multi-step reaction with 4 steps

1: acetic acid; bromine; hydrogen bromide / 1 h

2: sodium carbonate / N,N-dimethyl-formamide / 16 h / 50 °C

3: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1 h / 0 °C

4: caesium carbonate / N,N-dimethyl-formamide / 4 h / 80 °C

With hydrogen bromide; bromine; sodium carbonate; caesium carbonate; acetic acid; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; N,N-dimethyl-formamide;