2,4-DICHLORO-N-HYDROXYBENZENECARBOXIMIDOYL CHLORIDE

Base Information

• Chemical Name: 2,4-DICHLORO-N-HYDROXYBENZENECARBOXIMIDOYL CHLORIDE
• CAS No.: 29203-60-9
• Molecular Formula: C7H4 Cl3 N O
• Molecular Weight: 224.474
• Hs Code.: 2925290090
• Mol file: 29203-60-9.mol

Synonyms:Benzohydroximoylchloride, 2,4-dichloro- (8CI); Benzoyl chloride, 2,4-dichloro-, oxime(6CI,7CI); 2,4-Benzenehydroximic acid chloride;2,4-Dichloro-N-hydroxybenzenecarboximidoyl chloride;2,4-Dichlorobenzohydroxamoyl chloride; o,p-Dichlorobenzohydroximoyl chloride

Chemical Property of 2,4-DICHLORO-N-HYDROXYBENZENECARBOXIMIDOYL CHLORIDE

Chemical Property:

• Vapor Pressure: 3.51E-05mmHg at 25°C
• Melting Point: 93 °C
• Boiling Point: 339.7°Cat760mmHg
• Flash Point: 159.2°C
• PSA: 32.59000
• Density: 1.53g/cm³
• LogP: 3.36800

Purity/Quality:

98%min ^*data from raw suppliers

alpha,2,4-Trichlorobenzaldoxime ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: R34:Causes burns.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-DICHLORO-N-HYDROXYBENZENECARBOXIMIDOYL CHLORIDE

There total 3 articles about 2,4-DICHLORO-N-HYDROXYBENZENECARBOXIMIDOYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,4-dichlorobenzaldoxime (56843-28-8) → 2,4-dichloro-N-hydroxybenzenecarboximidoyl chloride (29203-60-9)

Guidance literature:

With N-chloro-succinimide; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

2,4-dichlorobenzaldeyhde (874-42-0) → 2,4-dichloro-N-hydroxybenzenecarboximidoyl chloride (29203-60-9)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NH₂OH*HCl; AcONa / ethanol / 12 h

2: N-chlorosuccinimide; pyridine / CHCl₃; tetrahydrofuran / 2 h

With pyridine; N-chloro-succinimide; hydroxylamine hydrochloride; sodium acetate; In tetrahydrofuran; ethanol; chloroform;

DOI:10.1016/S0960-894X(03)00130-6

Reference yield:

→ 2,4-dichloro-N-hydroxybenzenecarboximidoyl chloride (29203-60-9)

Guidance literature:

2,4-Dichlorbenzaldehydoxim, Cl2, S. 1952;

upstream raw materials:

2,4-dichlorobenzaldoxime

2,4-dichlorobenzaldeyhde

Downstream raw materials:

3-(2,4-dichloro-phenyl)-4-ethyl-5-phenyl-4,5-dihydro-[1,2,4]oxadiazole

3'-(2,4-dichloro-phenyl)-4'H-spiro[adamantane-2,5'-isoxazole]

3-(2,4-dichlorophenyl)-4-oxo-6-acetoxy-3a,4,6,6a-tetrahydrofuro<3,4-d>isoxazole

3'-(2,4-dichlorophenyl)spiro-3-one

Refernces

• 1、 Liu, Zhiyan,Cao, Jiangping,Yan, Xiaoting,Cheng, Wanqing,Wang, Xiaoguang,Yang, Ruige,Guo, Yong. "Discovery of Natural Product-Based Fungicides (II): Semisynthesis and Biological Activity of Sarisan Attached 3-Phenylisoxazolines as Antifungal Agents". . . Retrieved 2020/12/09.
• 2、 -. "NITROGENOUS TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE". Paragraph 00194. . Retrieved 2019/08/27.