2-(3-Chlorophenyl)pent-4-enoic acid

Base Information

Chemical Name:2-(3-Chlorophenyl)pent-4-enoic acid
CAS No.:619254-67-0
Molecular Formula:C₁₁H₁₁ClO₂
Molecular Weight:210.66
Hs Code.:
DSSTox Substance ID:DTXSID201265269

Synonyms:619254-67-0;SCHEMBL4023453;DTXSID201265269;AKOS017995080;3-Chloro-alpha-2-propen-1-ylbenzeneacetic acid

Suppliers and Price of 2-(3-Chlorophenyl)pent-4-enoic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(3-Chlorophenyl)pent-4-enoic acid

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:210.0447573
Heavy Atom Count:14
Complexity:215

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C=CCC(C1=CC(=CC=C1)Cl)C(=O)O

Technology Process of 2-(3-Chlorophenyl)pent-4-enoic acid

There total 6 articles about 2-(3-Chlorophenyl)pent-4-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 362483-68-9
methyl 2-(3-chlorophenyl)pent-4-enoate

: 619254-67-0
2-(3-chlorophenyl)pent-4-enoic acid

Guidance literature:: With lithium hydroxide; In methanol; at 20 ℃; for 20h;
DOI:10.1016/S0968-0896(03)00220-7

Reference yield: 78.0%

: 556-56-9
allyl iodid

: 1878-65-5
3-chlorophenylacetic acid

: 619254-67-0
2-(3-chlorophenyl)pent-4-enoic acid

Guidance literature:: 3-chlorophenylacetic acid; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.5h;

allyl iodid; In tetrahydrofuran; at 20 ℃; for 3h; Further stages.;
DOI:10.1016/j.bmcl.2006.05.034

Reference yield:

: 53088-68-9
methyl 3-chlorophenylacetate

: 619254-67-0
2-(3-chlorophenyl)pent-4-enoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / butyllithium; diisopropylamine / tetrahydrofuran; hexane / 2 h / -60 - 20 °C

2: 100 percent / aq. LiOH / methanol / 20 h / 20 °C

With lithium hydroxide; n-butyllithium; diisopropylamine; In tetrahydrofuran; methanol; hexane;
DOI:10.1016/S0968-0896(03)00220-7