4-(2-FURYL)ANILINE

Base Information

• Chemical Name: 4-(2-FURYL)ANILINE
• CAS No.: 59147-02-3
• Molecular Formula: C10H9NO
• Molecular Weight: 159.188
• Hs Code.: 2932190090
• Mol file: 59147-02-3.mol

Synonyms:p-2-Furylaniline;[4-(Furan-2-yl)phenyl]amine;4-(2-Furyl)aniline;2-(p-Aminophenyl)furan;Aniline,p-2-furyl- (7CI);

Chemical Property of 4-(2-FURYL)ANILINE

Chemical Property:

• Vapor Pressure: 0.00469mmHg at 25°C
• Melting Point: 55.5-57 °C
• Refractive Index: 1.593
• Boiling Point: 276.8 °C at 760 mmHg
• PKA: 3.99±0.10(Predicted)
• Flash Point: 121.2 °C
• PSA: 39.16000
• Density: 1.138 g/cm³
• LogP: 3.11000
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

99% ^*data from raw suppliers

4-(2-Furyl)aniline 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(2-FURYL)ANILINE

There total 11 articles about 4-(2-FURYL)ANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

fur-2-ylboronic acid (13331-23-2) + p-aminoiodobenzene (540-37-4) → 4-(furan-2-yl)aniline (59147-02-3)

Guidance literature:

With C₇H₁₀N₂*Pd⁽²⁺⁾*2Cl^(1-); potassium carbonate; In methanol; water; for 0.166667h; Reflux; Schlenk technique;

DOI:10.1016/j.catcom.2016.02.016

Reference yield: 92.0%

2-furyl(triphenylphosphine)gold(I) + p-aminoiodobenzene (540-37-4) → 4-(furan-2-yl)aniline (59147-02-3)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; water; at 20 ℃; for 12h;

DOI:10.1002/ejoc.201201720

Reference yield: 81.2%

2-(4-nitrophenyl)furan (28123-72-0) → 4-(furan-2-yl)aniline (59147-02-3)

Guidance literature:

With palladium on activated charcoal; hydrazine hydrate; In ethanol; at 20 ℃; for 0.5h;

upstream raw materials:

2-(4-nitrophenyl)furan

4-nitro-aniline

para-nitrophenyl triflate

p-aminoiodobenzene

Downstream raw materials:

N-(4-furan-2-ylphenyl)acetamide

Diethyl ester of N<4-(furyl-2)phenyl>aminomethylenemalonic acid

2-azido-4-(furan-2-yl)aniline

2-(4'-N,N-dimethylaminophenyl)furan