2-(2-(((4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyl-2-oxooxazolidin-3-yl)methyl)cyclohex-1-enyl)-5-methoxybenzaldehyde

Base Information

Chemical Name:2-(2-(((4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyl-2-oxooxazolidin-3-yl)methyl)cyclohex-1-enyl)-5-methoxybenzaldehyde
CAS No.:1402796-52-4
Molecular Formula:C₂₇H₂₅F₆NO₄
Molecular Weight:541.49
Hs Code.:

Synonyms:2-(2-(((4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyl-2-oxooxazolidin-3-yl)methyl)cyclohex-1-enyl)-5-methoxybenzaldehyde

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Chemical Property of 2-(2-(((4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyl-2-oxooxazolidin-3-yl)methyl)cyclohex-1-enyl)-5-methoxybenzaldehyde

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Technology Process of 2-(2-(((4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyl-2-oxooxazolidin-3-yl)methyl)cyclohex-1-enyl)-5-methoxybenzaldehyde

There total 5 articles about 2-(2-(((4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyl-2-oxooxazolidin-3-yl)methyl)cyclohex-1-enyl)-5-methoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₉H₁₆BrF₆NO₃

: 139962-95-1
2-formyl-4-methoxyphenylboronic acid

: 1402796-52-4
2-(2-(((4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyl-2-oxooxazolidin-3-yl)methyl)cyclohex-1-enyl)-5-methoxybenzaldehyde

Guidance literature:: With dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II); sodium carbonate; In 1,2-dimethoxyethane; water; Microwave irradiation;

Reference yield:

: 38127-47-8
2-bromocyclohex-1-ene-1-carbaldehyde

: 1402796-52-4
2-(2-(((4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyl-2-oxooxazolidin-3-yl)methyl)cyclohex-1-enyl)-5-methoxybenzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: sodium cyanoborohydride; acetic acid / dichloromethane

2: N-ethyl-N,N-diisopropylamine / dichloromethane

3: sodium carbonate / dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II) / 1,2-dimethoxyethane; water / Microwave irradiation

With sodium cyanoborohydride; sodium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II); In 1,2-dimethoxyethane; dichloromethane; water; 3: Suzuki Coupling;

Reference yield:

: 1152029-16-7
(1R,2S)-2-amino-1-[3,5-bis(trifluoromethyl)phenyl]propan-1-ol

: 1402796-52-4
2-(2-(((4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyl-2-oxooxazolidin-3-yl)methyl)cyclohex-1-enyl)-5-methoxybenzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: sodium cyanoborohydride; acetic acid / dichloromethane

2: N-ethyl-N,N-diisopropylamine / dichloromethane

3: sodium carbonate / dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II) / 1,2-dimethoxyethane; water / Microwave irradiation

With sodium cyanoborohydride; sodium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II); In 1,2-dimethoxyethane; dichloromethane; water; 3: Suzuki Coupling;