(3-Amino-1-benzofuran-2-YL)(4-hydroxyphenyl)methanone

Base Information

Chemical Name:(3-Amino-1-benzofuran-2-YL)(4-hydroxyphenyl)methanone
CAS No.:301538-52-3
Molecular Formula:C₁₅H₁₁NO₃
Molecular Weight:253.257
Hs Code.:
European Community (EC) Number:670-222-6

Synonyms:301538-52-3;(3-Aminobenzofuran-2-yl)(4-hydroxyphenyl)methanone;(3-AMINO-1-BENZOFURAN-2-YL)(4-HYDROXYPHENYL)METHANONE;AKOS024321070

Suppliers and Price of (3-Amino-1-benzofuran-2-YL)(4-hydroxyphenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3-Amino-1-benzofuran-2-YL)(4-hydroxyphenyl)methanone

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:253.07389321
Heavy Atom Count:19
Complexity:338

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=C(O2)C(=O)C3=CC=C(C=C3)O)N

Technology Process of (3-Amino-1-benzofuran-2-YL)(4-hydroxyphenyl)methanone

There total 4 articles about (3-Amino-1-benzofuran-2-YL)(4-hydroxyphenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 223788-34-9
2-(4-Methoxybenzoyl)-1-benzofuran-3-amine

: 301538-52-3
2-(4-Hydroxybenzoyl)-1-benzofuran-3-amine

Guidance literature:: With boron tribromide; In dichloromethane; at 20 ℃; for 7h;
DOI:10.1135/cccc20001093

Reference yield:

: 611-20-1
salicylonitrile

: 301538-52-3
2-(4-Hydroxybenzoyl)-1-benzofuran-3-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / K₂CO₃ / dimethylformamide / 2 h / 20 °C

2: 33 percent / CH₃ONa / methanol / 1 h / 20 °C

3: 87 percent / BBr₃ / CH₂Cl₂ / 7 h / 20 °C

With sodium methylate; boron tribromide; potassium carbonate; In methanol; dichloromethane; N,N-dimethyl-formamide; 1: Etherification / 2: Cyclization / 3: Ether cleavage; Demethylation;
DOI:10.1135/cccc20001093

Reference yield:

: 2632-13-5
2-Bromo-4'-methoxyacetophenone

: 301538-52-3
2-(4-Hydroxybenzoyl)-1-benzofuran-3-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / K₂CO₃ / dimethylformamide / 2 h / 20 °C

2: 33 percent / CH₃ONa / methanol / 1 h / 20 °C

3: 87 percent / BBr₃ / CH₂Cl₂ / 7 h / 20 °C

With sodium methylate; boron tribromide; potassium carbonate; In methanol; dichloromethane; N,N-dimethyl-formamide; 1: Etherification / 2: Cyclization / 3: Ether cleavage; Demethylation;
DOI:10.1135/cccc20001093