6,7-DICHLOROQUINOXALINE 98

Base Information

• Chemical Name: 6,7-DICHLOROQUINOXALINE 98
• CAS No.: 19853-64-6
• Molecular Formula: C8H4Cl2N2
• Molecular Weight: 199.039
• Hs Code.: 2933990090
• Mol file: 19853-64-6.mol

Synonyms:6,7-Dichloroquinoxaline;

Chemical Property of 6,7-DICHLOROQUINOXALINE 98

Chemical Property:

• Vapor Pressure: 0.000822mmHg at 25°C
• Melting Point: 210 °C
• Refractive Index: 1.67
• Boiling Point: 315.2 °C at 760 mmHg
• PKA: -1.22±0.30(Predicted)
• Flash Point: 173.6 °C
• PSA: 25.78000
• Density: 1.486 g/cm³
• LogP: 2.93660
• Storage Temp.: Room temperature.

Purity/Quality:

98%,99%, ^*data from raw suppliers

6,7-Dichloroquinoxaline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6,7-DICHLOROQUINOXALINE 98

There total 7 articles about 6,7-DICHLOROQUINOXALINE 98 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4,5-Dichloro-1,2-phenylenediamine (5348-42-5) + Glyoxal (131543-46-9,107-22-2) → 6,7‐dichloroquinoxaline (19853-64-6)

Guidance literature:

In ethanol; water; Reflux;

DOI:10.3390/molecules26113163

Reference yield: 78.0%

1-ethyl-piperidine (766-09-6) + 4,5-Dichloro-1,2-phenylenediamine (5348-42-5) → 6,7‐dichloroquinoxaline (19853-64-6)

Guidance literature:

With iron(II,III) oxide; oxygen; In dimethyl sulfoxide; for 48h; Irradiation;

Reference yield: 78.0%

4,5-Dichloro-1,2-phenylenediamine (5348-42-5) + glyoxal sodium bisulfite (517-21-5) → 6,7‐dichloroquinoxaline (19853-64-6)

Guidance literature:

With water; at 70 ℃; for 1h;

DOI:10.1039/a809838g

upstream raw materials:

6,7-dinitroquinoxaline

4,5-Dichloro-1,2-phenylenediamine

glyoxal sodium bisulfite

Glyoxal

Downstream raw materials:

1,2,3,4-tetrahydroquinoxaline

6-chloro-1,2,3,4-tetrahydroquinoxaline

6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione

Refernces

• 1、 Maciejewska, Agnieszka Monika,Paprocki, Daniel,Poznański, Jaros?aw,Speina, El?bieta,Winiewska‐szajewska, Maria. "Synthesis of novel halogenated heterocycles based on o‐phenylenediamine and their interactions with the catalytic subunit of protein kinase ck2". supporting information. . Retrieved 2021/06/09.
• 2、 Wang, Xiu-Zhi,Zeng, Cheng-Chu. "Iron-catalyzed Minisci acylation of N-heteroarenes with α-keto acids". supporting information. p. 1425 - 1430. Retrieved 2019/02/01.