517-21-5Relevant articles and documents
5a,10b-dihydrobenzofuro[2,3-b]benzofuran type compounds and related products from p-substituted phenols and glyoxal
Rahmatpour, Ali
, p. 1011 - 1016 (2010)
(Chemical Equation Presented) Condensation reactions of glyoxal with p-substituted phenol derivatives 1a-f have been carried out and the corresponding 5a,10b-dihydrobenzofuro[2,3-b]benzofuran 4a-f type compounds were obtained in good to excellent yields.
Kinetics, Mechanism, and Thermodynamics of Glyoxal-S(IV) Adduct Formation
Olson Terese M.,Hoffmann, Michael R.
, p. 533 - 540 (2007/10/02)
The reversible addition of glyoxal (ethanedial) and S(IV) to form glyoxal monobisulfite (GMBS) was studied spectrophotometrically over the pH range of 0.7-3.3.Far from equilibrium, the rate of GMBS formation is given by d/dt = (k1,appα1) + k2,appα2), where = + + , = + -> + 2->, α1 = ->/, and α2 = 2->/.The apparent rate constants, k1,app = 0.13 M-1 s-1 and k2,app = 2.08E3 M-1 s-1, are pH independent functions of the dehydration equilibrium constants of (CH(OH)2)2 and CHOCH(OH)2, and intrinsic rate constants for the reaction of HSO3- and SO32- with unhydrated and singly hydrated glyoxal.Glyoxal dibisulfite (GDBS) and GMBS were shown to dissociate with a rate given by d/dt = -1 + k"-1KD3 + (k'-2K'a2 + k"-2K"a2KD3)/+>>t + -3 + k-4Ka3/+>>t, where k-1 and k-2 correspond to the release of bisulfite and sulfite, respectively, from unhydrated and hydrated GMBS species; k-3 and k-4 correspond to the release of bisulfite and sulfite from GDBS; KD3 is the dehydration constant for GMBS; K'a2, K"a2, and Ka3 are acid dissociation constants.Stability constants for the formation of GMBS and GDBS were determined to be cK1 = ->/(-) = 2.81E4 M-1 and cK2 = -)2>/(->->) = 1.45E4 M-1 at 25 deg C and μ = 0.2 M.
