4-[N-methyl-N-(2-{[(4-methylphenyl)sulfonyloxy]ethyl}amino)]benzaldehyde

Base Information

• Chemical Name: 4-[N-methyl-N-(2-{[(4-methylphenyl)sulfonyloxy]ethyl}amino)]benzaldehyde
• CAS No.: 149265-10-1
• Molecular Formula: C₁₇H₁₉NO₄S
• Molecular Weight: 333.408
• Mol file: 149265-10-1.mol

Synonyms:4-[N-methyl-N-(2-{[(4-methylphenyl)sulfonyloxy]ethyl}amino)]benzaldehyde

Chemical Property of 4-[N-methyl-N-(2-{[(4-methylphenyl)sulfonyloxy]ethyl}amino)]benzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-[N-methyl-N-(2-{[(4-methylphenyl)sulfonyloxy]ethyl}amino)]benzaldehyde

There total 2 articles about 4-[N-methyl-N-(2-{[(4-methylphenyl)sulfonyloxy]ethyl}amino)]benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4-(N-methyl-N-hydroxyethylamino)benzaldehyde (1201-91-8) + p-toluenesulfonyl chloride (98-59-9) → 4-[N-methyl-N-(2-{[(4-methylphenyl)sulfonyloxy]ethyl}amino)]benzaldehyde (149265-10-1)

Guidance literature:

4-(N-methyl-N-hydroxyethylamino)benzaldehyde; With triethylamine; In dichloromethane; at 20 ℃; for 0.166667h;

p-toluenesulfonyl chloride; In dichloromethane; for 22h;

DOI:10.1016/j.dyepig.2017.01.009

Reference yield: 78.0%

4-(N-methyl-N-hydroxyethylamino)benzaldehyde (1201-91-8) + toluene-4-sulfonic acid (104-15-4) → 4-[N-methyl-N-(2-{[(4-methylphenyl)sulfonyloxy]ethyl}amino)]benzaldehyde (149265-10-1)

Guidance literature:

4-(N-methyl-N-hydroxyethylamino)benzaldehyde; With triethylamine; In dichloromethane; at 20 ℃; for 0.166667h;

toluene-4-sulfonic acid; In dichloromethane; at 20 ℃; for 72h;

DOI:10.1039/c9cc06729a

Reference yield: 90.0%

4-[N-methyl-N-(2-{[(4-methylphenyl)sulfonyloxy]ethyl}amino)]benzaldehyde (149265-10-1) → 4-((2-azidoethyl)(methyl)amino)benzaldehyde (1307899-00-8)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

DOI:10.1016/j.dyepig.2017.01.009

upstream raw materials:

4-(N-methyl-N-hydroxyethylamino)benzaldehyde

p-toluenesulfonyl chloride

toluene-4-sulfonic acid

Downstream raw materials:

(Z)-2-[N-methyl-N-(2'-fluoroethyl)-4'-aminostyryl]benzothiazole

(E)-2-[N-methyl-N-(2'-fluoroethyl)-4'-aminostyryl]benzothiazole

(E)-2-[N-methyl-N-(2'-tosyloxyethyl)-4'-aminostyryl]benzothiazole

(Z)-2-[N-methyl-N-(2'-fluoroethyl)-4'-aminostyryl]benzoxazole