Technology Process of 5,5'-(2,3,5,6-tetramethyl-1,4-phenylene)bis(methylene)bis(azanediyl)diisophthalic acid
There total 3 articles about 5,5'-(2,3,5,6-tetramethyl-1,4-phenylene)bis(methylene)bis(azanediyl)diisophthalic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
tetraethyl 5,5'-(2,3,5,6-tetramethyl-1,4-phenylene)bis(methylene)-bis(azanediyl)diisophthalate;
With
sodium hydroxide;
In
tetrahydrofuran; methanol; water;
at 100 ℃;
for 24h;
With
hydrogenchloride;
In
water;
pH=3-4;
DOI:10.1002/ejic.201402094
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: hydrogen bromide; acetic acid / water / 12.33 h / 85 - 95 °C
2.1: potassium carbonate / acetonitrile / 17 h / 10 - 20 °C / Inert atmosphere
3.1: sodium hydroxide / water; methanol; tetrahydrofuran / 24 h / 100 °C
3.2: pH 3-4
With
hydrogen bromide; potassium carbonate; acetic acid; sodium hydroxide;
In
tetrahydrofuran; methanol; water; acetonitrile;
DOI:10.1002/ejic.201402094
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sulfuric acid / 12 h / 100 °C / Reflux
2.1: potassium carbonate / acetonitrile / 17 h / 10 - 20 °C / Inert atmosphere
3.1: sodium hydroxide / water; methanol; tetrahydrofuran / 24 h / 100 °C
3.2: pH 3-4
With
sulfuric acid; potassium carbonate; sodium hydroxide;
In
tetrahydrofuran; methanol; water; acetonitrile;
DOI:10.1002/ejic.201402094
