3-benzoxy-1,2,4-trimethyl-11-phenylbenzofuro<2',3':4,5>pyrimido<1,6-a>benzimidazole

Base Information

• Chemical Name: 3-benzoxy-1,2,4-trimethyl-11-phenylbenzofuro<2',3':4,5>pyrimido<1,6-a>benzimidazole
• CAS No.: 74057-91-3
• Molecular Formula: C₃₂H₂₃N₃O₃
• Molecular Weight: 497.553
• Mol file: 74057-91-3.mol

Synonyms:3-benzoxy-1,2,4-trimethyl-11-phenylbenzofuro<2',3':4,5>pyrimido<1,6-a>benzimidazole

Chemical Property of 3-benzoxy-1,2,4-trimethyl-11-phenylbenzofuro<2',3':4,5>pyrimido<1,6-a>benzimidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-benzoxy-1,2,4-trimethyl-11-phenylbenzofuro<2',3':4,5>pyrimido<1,6-a>benzimidazole

There total 3 articles about 3-benzoxy-1,2,4-trimethyl-11-phenylbenzofuro<2',3':4,5>pyrimido<1,6-a>benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-amino-3-(benzimidazol-2-yl)-5-hydroxy-4,6,7-trimethylbenzofuran (74057-85-5) + benzoyl chloride (98-88-4) → 3-benzoxy-1,2,4-trimethyl-11-phenylbenzofuro<2',3':4,5>pyrimido<1,6-a>benzimidazole (74057-91-3)

Guidance literature:

In pyridine; at 20 ℃; for 1h;

DOI:10.1007/BF02401682

Reference yield:

1H-benzimidazol-2-acetonitrile (4414-88-4) → 3-benzoxy-1,2,4-trimethyl-11-phenylbenzofuro<2',3':4,5>pyrimido<1,6-a>benzimidazole (74057-91-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 64.5 percent / piperidine / dimethylformamide / 20 °C / overnight

2: 96 percent / pyridine / 1 h / 20 °C

With piperidine; In pyridine; N,N-dimethyl-formamide;

DOI:10.1007/BF02401682

Reference yield:

2,3,5-Trimethyl-1,4-benzoquinone (935-92-2) → 3-benzoxy-1,2,4-trimethyl-11-phenylbenzofuro<2',3':4,5>pyrimido<1,6-a>benzimidazole (74057-91-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 64.5 percent / piperidine / dimethylformamide / 20 °C / overnight

2: 96 percent / pyridine / 1 h / 20 °C

With piperidine; In pyridine; N,N-dimethyl-formamide;

DOI:10.1007/BF02401682

upstream raw materials:

2-amino-3-(benzimidazol-2-yl)-5-hydroxy-4,6,7-trimethylbenzofuran

benzoyl chloride

1H-benzimidazol-2-acetonitrile

2,3,5-Trimethyl-1,4-benzoquinone