1-(2-(2-((Allyloxy)methyl)-4-nitrophenoxy)ethyl)pyrrolidine

Base Information

Chemical Name:1-(2-(2-((Allyloxy)methyl)-4-nitrophenoxy)ethyl)pyrrolidine
CAS No.:937273-32-0
Molecular Formula:C₁₆H₂₂N₂O₄
Molecular Weight:306.362
Hs Code.:
DSSTox Substance ID:DTXSID501162777
Mol file:937273-32-0.mol

Synonyms:937273-32-0;1-(2-(2-((allyloxy)methyl)-4-nitrophenoxy)ethyl)pyrrolidine;SCHEMBL1098866;DTXSID501162777;1-[2-[4-Nitro-2-[(2-propen-1-yloxy)methyl]phenoxy]ethyl]pyrrolidine

Suppliers and Price of 1-(2-(2-((Allyloxy)methyl)-4-nitrophenoxy)ethyl)pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(2-(2-((ALLYLOXY)METHYL)-4-NITROPHENOXY)ETHYL)PYRROLIDINE 95.00%
5MG
$ 499.65

Total 1 raw suppliers

Chemical Property of 1-(2-(2-((Allyloxy)methyl)-4-nitrophenoxy)ethyl)pyrrolidine

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:306.15795719
Heavy Atom Count:22
Complexity:353

Purity/Quality:: 1-(2-(2-((ALLYLOXY)METHYL)-4-NITROPHENOXY)ETHYL)PYRROLIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=CCOCC1=C(C=CC(=C1)[N+](=O)[O-])OCCN2CCCC2

Technology Process of 1-(2-(2-((Allyloxy)methyl)-4-nitrophenoxy)ethyl)pyrrolidine

There total 5 articles about 1-(2-(2-((Allyloxy)methyl)-4-nitrophenoxy)ethyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 123-75-1
pyrrolidine

: 937273-31-9
1-(2-chloroethoxy)-2-((allyloxy)methyl)-4-nitrobenzene

: 937273-32-0
1-(2-{4-nitro-2-[(prop-2-en-1-yloxy)methyl]phenoxy}ethyl)pyrrolidine

Guidance literature:: In N,N-dimethyl acetamide; at 90 ℃; for 20h;
DOI:10.1021/jm201454n

Reference yield:

: 110837-53-1
2-(2-chloroethoxy)-5-nitrobenzaldehyde

: 937273-32-0
1-(2-{4-nitro-2-[(prop-2-en-1-yloxy)methyl]phenoxy}ethyl)pyrrolidine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium tetrahydroborate / tetrahydrofuran / 0 - 20 °C

2: tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide / 12 h / 20 °C

3: N,N-dimethyl acetamide / 20 h / 90 °C

With sodium tetrahydroborate; tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide; In tetrahydrofuran; N,N-dimethyl acetamide;
DOI:10.1021/jm200326p

Reference yield:

: 937273-30-8
[2-(2-chloroethoxy)-5-nitrophenyl]methanol

: 937273-32-0
1-(2-{4-nitro-2-[(prop-2-en-1-yloxy)methyl]phenoxy}ethyl)pyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide / 12 h / 20 °C

2: N,N-dimethyl acetamide / 20 h / 90 °C

With tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide; In N,N-dimethyl acetamide;
DOI:10.1021/jm200326p DOI:10.1021/jm201454n