Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Base Information

• Chemical Name: Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate
• CAS No.: 67625-37-0
• Molecular Formula: C10H9BrN2O2
• Molecular Weight: 269.098
• Hs Code.: 2933990090
• European Community (EC) Number: 860-906-4
• DSSTox Substance ID: DTXSID00428003
• Wikidata: Q72473224

Synonyms:6-Bromoimidazo[1,2-a]pyridine-2-carboxylicacid ethyl ester;Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate;imidazo[1,2-a]pyridine-2-carboxylic acid, 6-bromo-, ethyl ester;Ethyl6-bromoimidazo[1,2-a]pyridine-2-carboxylate;

Chemical Property of Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Chemical Property:

• Melting Point: 69-72℃
• Refractive Index: 1.637
• PKA: 1.58±0.50(Predicted)
• PSA: 43.60000
• Density: 1.6 g/cm³
• LogP: 2.27350
• Storage Temp.: 2-8°C
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 267.98474
• Heavy Atom Count: 15
• Complexity: 250

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl6-bromoimidazo[1,2-a]pyridine-2-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C1=CN2C=C(C=CC2=N1)Br

Technology Process of Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

There total 1 articles about Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

5-bromo-2-pyridylamine (1072-97-5) + ethyl Bromopyruvate (70-23-5) → ethyl 6-bromoimidazo<1,2-a>pyridine-2-carboxylate (67625-37-0)

Guidance literature:

With sodium hydrogencarbonate; In 1,4-dioxane; at 100 ℃; for 12h;

Reference yield: 100.0%

ethyl 6-bromoimidazo<1,2-a>pyridine-2-carboxylate (67625-37-0) + phenylboronic acid (98-80-6) → 6-phenylimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester (1173694-01-3)

Guidance literature:

With potassium fluoride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In water; acetonitrile; at 160 ℃; for 0.0833333h; Microwaves;

Reference yield: 100.0%

(4-methoxy-3,5-dimethylphenyl)boronic acid (301699-39-8) + ethyl 6-bromoimidazo<1,2-a>pyridine-2-carboxylate (67625-37-0) → 6-(4-methoxy-3,5-dimethylphenyl)-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester (1171094-69-1)

Guidance literature:

With potassium fluoride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In water; acetonitrile; at 160 ℃; for 0.0833333h; Microwaves;

upstream raw materials:

5-bromo-2-pyridylamine

ethyl Bromopyruvate

Downstream raw materials:

6-bromo-2-hydroxymethylimidazo<1,2-a>pyridine

6-bromo-imidazo[1,2-a]pyridine-2-carbohydrazide

6-bromoimidazo[1,2-a]pyridine-2-carboxylic acid

ethyl 6-(4-chlorophenyl)imidazo[1,2-a]pyridine-2-carboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 67625-37-0 Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send