7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde

Base Information

Chemical Name:7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
CAS No.:852054-42-3
Molecular Formula:C7H5 Br O3 S
Molecular Weight:249.085
Hs Code.:2934999090
DSSTox Substance ID:DTXSID40464445
Nikkaji Number:J3.176.182D
Wikidata:Q72454733
Mol file:852054-42-3.mol

Synonyms:852054-42-3;7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde;7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxaldehyde;7-BROMO-2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXINE-5-CARBOXALDEHYDE 97;5-bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-7-carbaldehyde;C7H5BrO3S;7-bromo-2H,3H-thieno[3,4-b][1,4]dioxine-5-carbaldehyde;SCHEMBL14852718;DTXSID40464445;AMY42152;BCP17569;MFCD08690306;AKOS015920293;DS-17037;B5396;CS-0103681;FT-0736063;EN300-1718462;5-bromo-3,4-ethylenedioxythiophene-2-carbaldehyde;A863653;Z1269175252;7-bromo-2,3-dihydrothieno[3,4-b]-1,4-dioxin-5-carboxaldehyde;7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde, AldrichCPR;7-Bromo-2 pound not3-dihydrothieno[3 pound not4-b][1 pound not4]dioxine-5-carbaldehyde

Suppliers and Price of 7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
250mg
$ 145.00

TCI Chemical
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxaldehyde >96.0%(GC)
1g
$ 261.00

TCI Chemical
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxaldehyde >96.0%(GC)
200mg
$ 75.00

SynQuest Laboratories
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxaldehyde 95.0%
1 g
$ 144.00

Crysdot
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde 95+%
5g
$ 379.00

Crysdot
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde 95+%
10g
$ 673.00

Biosynth Carbosynth
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
1 g
$ 189.00

Biosynth Carbosynth
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
500 mg
$ 110.00

Biosynth Carbosynth
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
250 mg
$ 62.50

Biosynth Carbosynth
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
5 g
$ 656.25

Total 34 raw suppliers

Chemical Property of 7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde

Chemical Property:

Vapor Pressure:4.09E-05mmHg at 25°C
Melting Point:141-142
Boiling Point:351.5ºC at 760 mmHg
Flash Point:166.4ºC
PSA：63.77000
Density:1.835g/cm3
LogP:2.09430
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:247.91428
Heavy Atom Count:12
Complexity:190

Purity/Quality:

97% ^*data from raw suppliers

7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=C(SC(=C2O1)C=O)Br

Technology Process of 7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde

There total 5 articles about 7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 204905-77-1
3,4-ethylenedioxythiophene-2-carboxaldehyde

: 852054-42-3
7-bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde

Guidance literature:: With N-Bromosuccinimide; In acetonitrile; at 20 ℃; for 60h;
DOI:10.1021/jo060687r

Reference yield:

: 126213-50-1
3,4-(ethylenedioxy)thiophene

: 852054-42-3
7-bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: BuLi / tetrahydrofuran

2: NBS; AcOH / CH₂Cl₂

With N-Bromosuccinimide; n-butyllithium; acetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1002/chem.200500889

Reference yield:

: 126213-50-1
3,4-(ethylenedioxy)thiophene

: 1392224-24-6
5-chloro-3,4-ethylenedioxythiophene-2-carbaldehyde

: 852054-42-3
7-bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: N-Bromosuccinimide / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere; Darkness

2: trichlorophosphate / 3 h / 50 °C / Inert atmosphere

With N-Bromosuccinimide; trichlorophosphate; In N,N-dimethyl-formamide; 2: Vilsmeier formylation;
DOI:10.1515/znb-2012-0402