(3R,6S)-6-((E)-(R)-2-Benzenesulfonyl-1,3-dimethyl-hex-4-enyl)-2-(2-chloro-ethoxy)-3-methoxy-tetrahydro-pyran-4-one

Base Information Edit

Chemical Name:(3R,6S)-6-((E)-(R)-2-Benzenesulfonyl-1,3-dimethyl-hex-4-enyl)-2-(2-chloro-ethoxy)-3-methoxy-tetrahydro-pyran-4-one
CAS No.:91365-89-8
Molecular Formula:C₂₂H₃₁ClO₆S
Molecular Weight:459.004
Hs Code.:
Mol file:91365-89-8.mol

Synonyms:(3R,6S)-6-((E)-(R)-2-Benzenesulfonyl-1,3-dimethyl-hex-4-enyl)-2-(2-chloro-ethoxy)-3-methoxy-tetrahydro-pyran-4-one

Suppliers and Price of (3R,6S)-6-((E)-(R)-2-Benzenesulfonyl-1,3-dimethyl-hex-4-enyl)-2-(2-chloro-ethoxy)-3-methoxy-tetrahydro-pyran-4-one

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3R,6S)-6-((E)-(R)-2-Benzenesulfonyl-1,3-dimethyl-hex-4-enyl)-2-(2-chloro-ethoxy)-3-methoxy-tetrahydro-pyran-4-one Edit

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3R,6S)-6-((E)-(R)-2-Benzenesulfonyl-1,3-dimethyl-hex-4-enyl)-2-(2-chloro-ethoxy)-3-methoxy-tetrahydro-pyran-4-one

There total 11 articles about (3R,6S)-6-((E)-(R)-2-Benzenesulfonyl-1,3-dimethyl-hex-4-enyl)-2-(2-chloro-ethoxy)-3-methoxy-tetrahydro-pyran-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-73-2
acrolein dimer

: 91365-89-8
(3R,6S)-6-((E)-(R)-2-Benzenesulfonyl-1,3-dimethyl-hex-4-enyl)-2-(2-chloro-ethoxy)-3-methoxy-tetrahydro-pyran-4-one

Guidance literature:: Multi-step reaction with 9 steps

1: tetrahydrofuran; hexane / Ambient temperature

2: 92 percent / pyridine / CH₂Cl₂ / 0.5 h / 0 °C

4: MCPBA / CH₂Cl₂ / 72 h / Ambient temperature

5: 2. potassium fluoride / 1. -78 deg C/THF/5 min 2. MeOH/1 h/room temperature

6: 1. n-BuLi / 1. THF-HMPA, -78 deg C, 10 min 2. 0 deg C, 30 min

8: 92 percent / methyl orthoformate, d,l-camphersulphonic acid / 18 h / 80 °C

9: 5.6 g / CrO₃*2Py / CH₂Cl₂ / 0.5 h / Ambient temperature

With pyridine; potassium fluoride; n-butyllithium; 10-camphorsufonic acid; dipyridine chromium trioxide; 3-chloro-benzenecarboperoxoic acid; trimethyl orthoformate; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/jo00193a015

Reference yield:

: 62762-44-1
lithium bis(trimethylsilyl)(phenylthio)methylide

: 91365-89-8
(3R,6S)-6-((E)-(R)-2-Benzenesulfonyl-1,3-dimethyl-hex-4-enyl)-2-(2-chloro-ethoxy)-3-methoxy-tetrahydro-pyran-4-one

Guidance literature:: Multi-step reaction with 9 steps

1: tetrahydrofuran; hexane / Ambient temperature

2: 92 percent / pyridine / CH₂Cl₂ / 0.5 h / 0 °C

4: MCPBA / CH₂Cl₂ / 72 h / Ambient temperature

5: 2. potassium fluoride / 1. -78 deg C/THF/5 min 2. MeOH/1 h/room temperature

6: 1. n-BuLi / 1. THF-HMPA, -78 deg C, 10 min 2. 0 deg C, 30 min

8: 92 percent / methyl orthoformate, d,l-camphersulphonic acid / 18 h / 80 °C

9: 5.6 g / CrO₃*2Py / CH₂Cl₂ / 0.5 h / Ambient temperature

With pyridine; potassium fluoride; n-butyllithium; 10-camphorsufonic acid; dipyridine chromium trioxide; 3-chloro-benzenecarboperoxoic acid; trimethyl orthoformate; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/jo00193a015