C₁₄H₂₃ClO₂

Base Information

• Chemical Name: C₁₄H₂₃ClO₂
• CAS No.: 250328-17-7
• Molecular Formula: C₁₄H₂₃ClO₂
• Molecular Weight: 258.788
• Mol file: 250328-17-7.mol

Synonyms:C₁₄H₂₃ClO₂

Chemical Property of C₁₄H₂₃ClO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₂₃ClO₂

There total 1 articles about C₁₄H₂₃ClO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

2-(but-3-yn-1-yloxy)tetrahydropyran (40365-61-5) + 1-chloro-5-iodopentane (60274-60-4) → C14H23ClO2 (250328-17-7)

Guidance literature:

2-(but-3-yn-1-yloxy)tetrahydropyran; With n-butyllithium; In tetrahydrofuran; at 20 ℃; for 0.5h;

1-chloro-5-iodopentane; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at 20 ℃; for 2h; Further stages.;

DOI:10.1021/ol990114j

Reference yield: 82.0%

C14H23ClO2 (250328-17-7) → C14H23IO2 (250328-11-1)

Guidance literature:

With sodium iodide; In acetone; for 48h; Heating;

DOI:10.1021/ol990114j

Reference yield:

C14H23ClO2 (250328-17-7) → (3E, 13Z)-3,13-octadecadien-1-yl acetate (53120-26-6)

Guidance literature:

Multi-step reaction with 6 steps

1: 82 percent / NaI / acetone / 48 h / Heating

2: 66 percent / LDA / tetrahydrofuran; hexamethylphosphoric acid triamide / -78 - -50 °C

3: 84 percent / p-TsOH / methanol / 16 h / 20 °C

4: 97 percent / Na(Hg); Na₂HPO₄ / methanol / 21 h / 20 °C

5: 83 percent / Na; NH₃ / tetrahydrofuran / 4 h

6: 95 percent / DMAP; Et₃N / CH₂Cl₂

With dmap; disodium hydrogenphosphate; sodium amalgam; ammonia; sodium; toluene-4-sulfonic acid; triethylamine; sodium iodide; lithium diisopropyl amide; In tetrahydrofuran; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; dichloromethane; acetone;

DOI:10.1021/ol990114j

upstream raw materials:

2-(but-3-yn-1-yloxy)tetrahydropyran

1-chloro-5-iodopentane

Downstream raw materials:

C₁₄H₂₃IO₂

C₂₉H₄₄SO₄

C₂₄H₃₆SO₃

(3E, 13Z)-3,13-octadecadien-1-yl acetate

Refernces