40365-61-5

Basic information

• Product Name: 2-(3-BUTYNYLOXY)TETRAHYDRO-2 H-PYRAN
• Synonyms: 3-Butynyl tetrahydro-2H-pyran-2-yl ether;2-(3-BUTYNYLOXY)TETRAHYDRO-2 H-PYRAN;4-[(Tetrahydro-2H-pyran-2-yl)oxy]-1-butyne;2H-Pyran, 2-(3-butynyloxy)tetrahydro-;2-(3-Butynyloxy)tetrahydropyran, 98%;2-but-3-ynoxyoxane;2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran;4-[(Tetrahydro-2H-pyran-2-yl)oxy]but-1-yne, 2-[(But-3-yn-1-yl)oxy]oxane
• CAS NO: 40365-61-5
• Molecular Formula: C₉H₁₄O₂
• Molecular Weight: 154.21
• Product Categories: Organoborons;Pyran;Building Blocks;Heterocyclic Building Blocks;Pyrans
• Mol File: 40365-61-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 92-95 °C18 mm Hg(lit.)
• Flash Point: 163 °F
• Appearance: /
• Density: 0.984 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.338mmHg at 25°C
• Refractive Index: n20/D 1.457(lit.)
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Sparingly), Ethyl Acetate (Slightly)
• CAS DataBase Reference: 2-(3-BUTYNYLOXY)TETRAHYDRO-2 H-PYRAN(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-BUTYNYLOXY)TETRAHYDRO-2 H-PYRAN(40365-61-5)
• EPA Substance Registry System: 2-(3-BUTYNYLOXY)TETRAHYDRO-2 H-PYRAN(40365-61-5)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 23-26-28-37/39
• WGK Germany: 3
• Hazardous Substances Data: 40365-61-5(Hazardous Substances Data)

Usage

Uses

2-(3-Butynyloxy)tetrahydropyran is used as a reagent in the synthesis of Phomoidride D, a bridged, polycyclic, natural compound that has the ability to inhibit squalene synthase and can be used as an antihypercholesterolemic agent. It is also used as a reagent to prepare Rugulactone, a natural compound that is isolated from Cryptocarya rugulosa.

InChI:InChI=1/C9H14O2/c1-2-3-7-10-9-6-4-5-8-11-9/h1,9H,3-8H2

Downstream Products

• 1002-28-4 3-hexyn-1-ol 
• 622-38-8 Ethyl phenyl sulfide 
• 882-33-7 diphenyldisulfane 
• 256510-57-3 O-(2-tetrahydropyranyl)-5-(3,5-dimethoxyphenyl)-3-pentyn-1-ol 
• 28856-77-1 3-phenylthiopyridine 
• 516457-54-8 tert-Butyl-[(2S,3S,5S)-5-[(Z)-3-chloro-6-(tetrahydro-pyran-2-yloxy)-hex-3-enyl]-2-(4-methoxy-benzyloxymethyl)-tetrahydro-furan-3-yloxy]-dimethyl-silane 
• 287198-97-4 tert-Butyl-dimethyl-{4-[(3E,5E,7E)-10-(tetrahydro-pyran-2-yloxy)-deca-3,5,7-trienyl]-phenoxy}-silane 
• 89471-85-2 (E)-(5R,6S)-6-Benzyloxy-8-methyl-1-(tetrahydro-pyran-2-yloxy)-non-3-en-5-ol 
• 101039-12-7 (E)-(3R,6R)-6-Benzyloxy-2-but-3-enyl-8-methyl-3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-non-4-enoic acid ethyl ester 
• 89471-82-9 (5R,6S)-6-Benzyloxy-8-methyl-1-(tetrahydro-pyran-2-yloxy)-non-3-yn-5-ol 
• 1018968-22-3 N-(1-phenyl-5-(tetrahydro-2H-pyran-2-yloxy)pent-2-ynyl)benzeneamine 
• 1239319-31-3 2-(8-(4-methoxyphenoxy)oct-3-ynyloxy)tetrahydro-2H-pyran 
• 1270183-14-6 3-(4-(tetrahydro-2H-pyran-2-yloxy)but-1-ynyl)cyclohex-2-enone 
• 1270183-46-4 (3R)-3-(but-3-enyl)-3-(4-(tetrahydro-2H-pyran-2-yloxy)but-1-ynyl)cyclohexanone