diphenylmethyl (6R,7R)-7-formamido-3-(4-nitrophenoxycarbonyloxy)methyl-Δ³-cephem-4-carboxylate

Base Information

• Chemical Name: diphenylmethyl (6R,7R)-7-formamido-3-(4-nitrophenoxycarbonyloxy)methyl-Δ³-cephem-4-carboxylate
• CAS No.: 167695-37-6
• Molecular Formula: C₂₉H₂₃N₃O₉S
• Molecular Weight: 589.582
• Mol file: 167695-37-6.mol

Synonyms:diphenylmethyl (6R,7R)-7-formamido-3-(4-nitrophenoxycarbonyloxy)methyl-Δ³-cephem-4-carboxylate

Chemical Property of diphenylmethyl (6R,7R)-7-formamido-3-(4-nitrophenoxycarbonyloxy)methyl-Δ³-cephem-4-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of diphenylmethyl (6R,7R)-7-formamido-3-(4-nitrophenoxycarbonyloxy)methyl-Δ³-cephem-4-carboxylate

There total 1 articles about diphenylmethyl (6R,7R)-7-formamido-3-(4-nitrophenoxycarbonyloxy)methyl-Δ³-cephem-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-Nitrophenyl chloroformate (7693-46-1) + diphenylmethyl 7-formamido-3-hydroxymethyl-Δ3-cephem-4-carboxylate (49599-37-3) → diphenylmethyl (6R,7R)-7-formamido-3-(4-nitrophenoxycarbonyloxy)methyl-Δ3-cephem-4-carboxylate (167695-37-6)

Guidance literature:

With pyridine; In tetrahydrofuran; acetonitrile; at 0 ℃; for 0.666667h;

DOI:10.1248/cpb.43.1031

Reference yield: 98.0%

diphenylmethyl (6R,7R)-7-formamido-3-(4-nitrophenoxycarbonyloxy)methyl-Δ3-cephem-4-carboxylate (167695-37-6) → (6R,7R)-7-formamido-3-(4-nitrophenoxycarbonyloxy)methyl-Δ3-cephem-4-carboxylic acid (142967-17-7)

Guidance literature:

With methoxybenzene; trifluoroacetic acid; at 0 ℃; for 0.666667h;

DOI:10.1248/cpb.43.1031

upstream raw materials:

4-Nitrophenyl chloroformate

diphenylmethyl 7-formamido-3-hydroxymethyl-Δ³-cephem-4-carboxylate

Downstream raw materials:

(6R,7R)-7-formamido-3-(4-nitrophenoxycarbonyloxy)methyl-Δ³-cephem-4-carboxylic acid