2-methyl-2-(4-trifluoromethyl-benzenesulfonyl)-propionic acid chloride

Base Information

• Chemical Name: 2-methyl-2-(4-trifluoromethyl-benzenesulfonyl)-propionic acid chloride
• CAS No.: 1004770-41-5
• Molecular Formula: C₁₁H₁₀ClF₃O₃S
• Molecular Weight: 314.713

Synonyms:2-methyl-2-(4-trifluoromethyl-benzenesulfonyl)-propionic acid chloride

Chemical Property of 2-methyl-2-(4-trifluoromethyl-benzenesulfonyl)-propionic acid chloride

Chemical Property:

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Technology Process of 2-methyl-2-(4-trifluoromethyl-benzenesulfonyl)-propionic acid chloride

There total 1 articles about 2-methyl-2-(4-trifluoromethyl-benzenesulfonyl)-propionic acid chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-2-((4-(trifluoromethyl)phenyl)sulfonyl)propanoic acid → 2-methyl-2-(4-trifluoromethyl-benzenesulfonyl)-propionic acid chloride (1004770-41-5)

Guidance literature:

With thionyl chloride; at 80 ℃; for 2h;

Reference yield:

3-amino-5-tert-butylisoxazole (55809-36-4) + 2-methyl-2-(4-trifluoromethyl-benzenesulfonyl)-propionic acid chloride (1004770-41-5) → N-(5-tert-Butyl-isoxazol-3-yl)-2-methyl-2-(4-trifluoromethylbenzenesulfonyl)-propionamide

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 18h;

Reference yield:

2-methyl-2-(4-trifluoromethyl-benzenesulfonyl)-propionic acid chloride (1004770-41-5) + N'-hydroxypivalimidamide (42956-75-2) → 3-tert-butyl-5-[1-methyl-1-(4-trifluoromethyl-benzenesulfonyl)-ethyl]-[1,2,4]oxadiazole (1196103-39-5)

Guidance literature:

With pyridine; at 110 ℃; for 3h; Molecular sieves;

Downstream raw materials:

3-tert-butyl-5-[1-methyl-1-(4-trifluoromethyl-benzenesulfonyl)-ethyl]-[1,2,4]oxadiazole

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