3-NITRO-5-(PYRROLIDIN-1-YLCARBONYL)BENZENEBORONIC ACID

Base Information

• Chemical Name: 3-NITRO-5-(PYRROLIDIN-1-YLCARBONYL)BENZENEBORONIC ACID
• CAS No.: 871332-81-9
• Molecular Formula: C11H13 B N2 O5
• Molecular Weight: 264.046
• Hs Code.: 2933990090
• Mol file: 871332-81-9.mol

Synonyms:Boronicacid, [3-nitro-5-(1-pyrrolidinylcarbonyl)phenyl]- (9CI)

Chemical Property of 3-NITRO-5-(PYRROLIDIN-1-YLCARBONYL)BENZENEBORONIC ACID

Chemical Property:

• Vapor Pressure: 2.82E-12mmHg at 25°C
• Melting Point: 181-183oC
• Boiling Point: 535oC at 760 mmHg
• Flash Point: 277.4oC
• PSA: 106.59000
• Density: 1.42g/cm3
• LogP: -0.02830
• Storage Temp.: Keep Cold

Purity/Quality:

98.5% ^*data from raw suppliers

3-Nitro-5-(pyrrolidin-1-ylcarbonyl)benzeneboronic acid 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-NITRO-5-(PYRROLIDIN-1-YLCARBONYL)BENZENEBORONIC ACID

There total 1 articles about 3-NITRO-5-(PYRROLIDIN-1-YLCARBONYL)BENZENEBORONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

pyrrolidine (123-75-1) + 3-bromo-5-nitro-benzoic acid (6307-83-1) → C11H13BN2O5 (871332-81-9)

Guidance literature:

pyrrolidine; 3-bromo-5-nitro-benzoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In acetonitrile;

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; bis(pinacol)diborane; In 2-methyltetrahydrofuran;

With hydrogenchloride; sodium periodate; In 2-methyltetrahydrofuran; water;

DOI:10.1021/op100267p

upstream raw materials:

pyrrolidine

3-bromo-5-nitro-benzoic acid

Refernces