METHYL 4-BROMO-3-METHOXYBENZOATE

Base Information

• Chemical Name: METHYL 4-BROMO-3-METHOXYBENZOATE
• CAS No.: 17100-63-9
• Molecular Formula: C9H9BrO3
• Molecular Weight: 245.073
• Hs Code.: 2918990090
• Mol file: 17100-63-9.mol

Synonyms:m-Anisicacid, 4-bromo-, methyl ester (8CI);4-Bromo-3-methoxybenzoic acid methyl ester;Methyl 4-bromo-3-(methyloxy)benzoate;Methyl 4-bromo-3-methoxybenzoate;

Chemical Property of METHYL 4-BROMO-3-METHOXYBENZOATE

Chemical Property:

• Vapor Pressure: 0.001mmHg at 25°C
• Melting Point: 58-61°C
• Refractive Index: 1.538
• Boiling Point: 306.008 °C at 760 mmHg
• Flash Point: 138.869 °C
• PSA: 35.53000
• Density: 1.462g/cm³
• LogP: 2.24430
• Storage Temp.: Keep Cold

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methyl4-Bromo-3-methoxybenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL 4-BROMO-3-METHOXYBENZOATE

There total 11 articles about METHYL 4-BROMO-3-METHOXYBENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ methyl 4-bromo-3-methoxybenzoate (17100-63-9)

Guidance literature:

Reference yield: 99.0%

methyl 4-bromo-3-hydroxybenzoate (106291-80-9) + dimethyl sulfate (77-78-1) → methyl 4-bromo-3-methoxybenzoate (17100-63-9)

Guidance literature:

With potassium carbonate; In acetone; for 3h; Heating / reflux;

Reference yield: 91.0%

methyl 4-bromo-3-hydroxybenzoate (106291-80-9) + methyl iodide (74-88-4) → methyl 4-bromo-3-methoxybenzoate (17100-63-9)

Guidance literature:

methyl 4-bromo-3-hydroxybenzoate; With potassium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 4h;

methyl iodide; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 10h;

DOI:10.1039/c6tc00153j

upstream raw materials:

diazomethane

methyl 4-bromo-3-hydroxybenzoate

dimethyl sulfate

4-bromo-3-hydroxybenzoic acid

Downstream raw materials:

Bis-(2-methoxy-4-methoxycarbonylphenyl)-aether

3-Methoxy-4-cyanobenzoyl chloride

4-Cyano-3-methoxybenzoic acid

4-Cyano-3-methoxy-benzoic acid methyl ester

Refernces

• 1、 -. "CANCER TREATMENTS TARGETING CANCER STEM CELLS". Paragraph 0331; 0623-0625. . Retrieved 2019/11/19.
• 2、 Jiao, Yan,Li, Ming,Wang, Ning,Lu, Tao,Zhou, Liang,Huang, Yan,Lu, Zhiyun,Luo, Daibing,Pu, Xuemei. "A facile color-tuning strategy for constructing a library of Ir(III) complexes with fine-tuned phosphorescence from bluish green to red using a synergetic substituent effect of -OCH3 and -CN at only the C-ring of C∧N ligand". supporting information. p. 4269 - 4277. Retrieved 2016/06/01.