6-(4-bromophenyl)-2-(ethylthio)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine

Base Information

• Chemical Name: 6-(4-bromophenyl)-2-(ethylthio)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine
• CAS No.: 1605289-09-5
• Molecular Formula: C₂₀H₁₆BrN₃S₂
• Molecular Weight: 442.403
• Mol file: 1605289-09-5.mol

Synonyms:6-(4-bromophenyl)-2-(ethylthio)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine

Chemical Property of 6-(4-bromophenyl)-2-(ethylthio)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-(4-bromophenyl)-2-(ethylthio)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine

There total 2 articles about 6-(4-bromophenyl)-2-(ethylthio)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

6-(4-bromophenyl)-4-imino-7-phenylpyrrolo[2,3-d][1,3]thiazin-2(1H,4H,7H)-thione (1605289-04-0) + ethyl iodide (75-03-6) → 6-(4-bromophenyl)-2-(ethylthio)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine (1605289-09-5)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; for 24h;

DOI:10.1016/j.ejmech.2014.03.068

Reference yield:

2-amino-5-(4-bromo-phenyl)-1-phenyl-1H-pyrrole-3-carbonitrile (748810-19-7) → 6-(4-bromophenyl)-2-(ethylthio)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine (1605289-09-5)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 3 h / Reflux

2: sodium hydride / N,N-dimethyl-formamide / 24 h

With pyridine; sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1016/j.ejmech.2014.03.068

upstream raw materials:

6-(4-bromophenyl)-4-imino-7-phenylpyrrolo[2,3-d][1,3]thiazin-2(1H,4H,7H)-thione

ethyl iodide

2-amino-5-(4-bromo-phenyl)-1-phenyl-1H-pyrrole-3-carbonitrile