N-<4-(1H-imidazol-1-yl)butyl>-6-<(4-isopropylphenyl)-amino>-3-pyridinecarboxamide

Base Information

Chemical Name:N-<4-(1H-imidazol-1-yl)butyl>-6-<(4-isopropylphenyl)-amino>-3-pyridinecarboxamide
CAS No.:107962-03-8
Molecular Formula:C₂₂H₂₇N₅O
Molecular Weight:377.489
Hs Code.:

Synonyms:N-<4-(1H-imidazol-1-yl)butyl>-6-<(4-isopropylphenyl)-amino>-3-pyridinecarboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-<4-(1H-imidazol-1-yl)butyl>-6-<(4-isopropylphenyl)-amino>-3-pyridinecarboxamide

Chemical Property:

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Technology Process of N-<4-(1H-imidazol-1-yl)butyl>-6-<(4-isopropylphenyl)-amino>-3-pyridinecarboxamide

There total 3 articles about N-<4-(1H-imidazol-1-yl)butyl>-6-<(4-isopropylphenyl)-amino>-3-pyridinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5326-23-8
6-Chloro-3-pyridinecarboxylic acid

: 107962-03-8
N-<4-(1H-imidazol-1-yl)butyl>-6-<(4-isopropylphenyl)-amino>-3-pyridinecarboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / 3.5 h / Heating

2: acetonitrile / 1 h / 60 °C

3: 89.9 percent / 2-methoxy-ethanol / 10 h / Heating

With thionyl chloride; In 2-methoxy-ethanol; acetonitrile;
DOI:10.1021/jo00388a023

Reference yield:

: 58757-38-3
6-Chloronicotinoyl chloride

: 107962-03-8
N-<4-(1H-imidazol-1-yl)butyl>-6-<(4-isopropylphenyl)-amino>-3-pyridinecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 1 h / 60 °C

2: 89.9 percent / 2-methoxy-ethanol / 10 h / Heating

In 2-methoxy-ethanol; acetonitrile;
DOI:10.1021/jo00388a023

Reference yield:

: 67319-76-0
4-(1H-imidazol-1-yl)butanamine

: 107962-03-8
N-<4-(1H-imidazol-1-yl)butyl>-6-<(4-isopropylphenyl)-amino>-3-pyridinecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 1 h / 60 °C

2: 89.9 percent / 2-methoxy-ethanol / 10 h / Heating

In 2-methoxy-ethanol; acetonitrile;
DOI:10.1021/jo00388a023