phenyl (4-methoxy-7-morpholin-4-yl-benzo[d]thiazol-2-yl)carbamate

Base Information

• Chemical Name: phenyl (4-methoxy-7-morpholin-4-yl-benzo[d]thiazol-2-yl)carbamate
• CAS No.: 383869-80-5
• Molecular Formula: C₁₉H₁₉N₃O₄S
• Molecular Weight: 385.444
• Mol file: 383869-80-5.mol

Synonyms:phenyl (4-methoxy-7-morpholin-4-yl-benzo[d]thiazol-2-yl)carbamate

Chemical Property of phenyl (4-methoxy-7-morpholin-4-yl-benzo[d]thiazol-2-yl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of phenyl (4-methoxy-7-morpholin-4-yl-benzo[d]thiazol-2-yl)carbamate

There total 7 articles about phenyl (4-methoxy-7-morpholin-4-yl-benzo[d]thiazol-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl-amine (383865-57-4) + phenyl chloroformate (1885-14-9) → phenyl (4-methoxy-7-morpholin-4-yl-benzo[d]thiazol-2-yl)carbamate (383869-80-5)

Guidance literature:

With pyridine; In dichloromethane;

DOI:10.1155/2017/4852537

Reference yield: 75.0%

4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl-amine (383865-57-4) → phenyl (4-methoxy-7-morpholin-4-yl-benzo[d]thiazol-2-yl)carbamate (383869-80-5)

Guidance literature:

Reference yield:

4-(4-methoxy-3-nitrophenyl)morpholine (383870-96-0) → phenyl (4-methoxy-7-morpholin-4-yl-benzo[d]thiazol-2-yl)carbamate (383869-80-5)

Guidance literature:

Multi-step reaction with 4 steps

1: hydrogenchloride; tin / water; ethanol

2: acetone

3: sodium methylate; methanol

4: pyridine / dichloromethane

With pyridine; hydrogenchloride; methanol; tin; sodium methylate; In ethanol; dichloromethane; water; acetone;

DOI:10.1155/2017/4852537

upstream raw materials:

4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl-amine

phenyl chloroformate

4-bromo-1-methoxy-2-nitrobenzene

4-(4-methoxy-3-nitrophenyl)morpholine

Downstream raw materials:

Tozadenant