4,4'-toluene-p-sulphonyliminodibutyl bismethanesulphonate

Base Information

• Chemical Name: 4,4'-toluene-p-sulphonyliminodibutyl bismethanesulphonate
• CAS No.: 121712-13-8
• Molecular Formula: C₁₇H₂₉NO₈S₃
• Molecular Weight: 471.617
• Mol file: 121712-13-8.mol

Synonyms:4,4'-toluene-p-sulphonyliminodibutyl bismethanesulphonate

Chemical Property of 4,4'-toluene-p-sulphonyliminodibutyl bismethanesulphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4'-toluene-p-sulphonyliminodibutyl bismethanesulphonate

There total 3 articles about 4,4'-toluene-p-sulphonyliminodibutyl bismethanesulphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

N,N'-bis(4-hydroxybutyl)toluene-p-sulphonamide (121712-12-7) + methanesulfonyl chloride (124-63-0) → 4,4'-toluene-p-sulphonyliminodibutyl bismethanesulphonate (121712-13-8)

Guidance literature:

With triethylamine; In dichloromethane; at -5 - 0 ℃; for 1h;

Reference yield:

4-Methyl-N,N-bis-[4-(tetrahydro-pyran-2-yloxy)-butyl]-benzenesulfonamide (121712-11-6) → 4,4'-toluene-p-sulphonyliminodibutyl bismethanesulphonate (121712-13-8)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. HCl / methanol

2: 74 percent / NEt₃ / CH₂Cl₂ / 1 h / -5 - 0 °C

With hydrogenchloride; triethylamine; In methanol; dichloromethane;

Reference yield:

toluene-4-sulfonamide (70-55-3) → 4,4'-toluene-p-sulphonyliminodibutyl bismethanesulphonate (121712-13-8)

Guidance literature:

Multi-step reaction with 3 steps

1: NaH / dimethylformamide / 70 °C

2: TsOH / ethanol

3: Et₃N / CH₂Cl₂

With sodium hydride; toluene-4-sulfonic acid; triethylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/S0040-4039(00)82312-6

upstream raw materials:

N,N'-bis(4-hydroxybutyl)toluene-p-sulphonamide

methanesulfonyl chloride

4-Methyl-N,N-bis-[4-(tetrahydro-pyran-2-yloxy)-butyl]-benzenesulfonamide

toluene-4-sulfonamide

Downstream raw materials:

(S)-ethyl 1,6,11-tritosyl-1,6,11-triazacyclohexadecane-12-carboxylate

[(S)-1,6,11-Tris-(toluene-4-sulfonyl)-1,6,11-triaza-cyclopentadec-2-yl]-methanol