N-(2-([4-(4-fluorobenzyl)piperidin-1-yl]methyl)benzimidazol-5-yl)methanesulfonamide

Base Information

Chemical Name:N-(2-([4-(4-fluorobenzyl)piperidin-1-yl]methyl)benzimidazol-5-yl)methanesulfonamide
CAS No.:1080622-46-3
Molecular Formula:C₂₁H₂₅FN₄O₂S
Molecular Weight:416.52
Hs Code.:

Synonyms:N-(2-([4-(4-fluorobenzyl)piperidin-1-yl]methyl)benzimidazol-5-yl)methanesulfonamide

Suppliers and Price of N-(2-([4-(4-fluorobenzyl)piperidin-1-yl]methyl)benzimidazol-5-yl)methanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2-([4-(4-fluorobenzyl)piperidin-1-yl]methyl)benzimidazol-5-yl)methanesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(2-([4-(4-fluorobenzyl)piperidin-1-yl]methyl)benzimidazol-5-yl)methanesulfonamide

There total 8 articles about N-(2-([4-(4-fluorobenzyl)piperidin-1-yl]methyl)benzimidazol-5-yl)methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1310689-11-2
2-[4-(4-fluorobenzyl)piperidin-1-yl]methyl-5-aminobenzimidazol

: 124-63-0
methanesulfonyl chloride

: 1080622-46-3
N-(2-([4-(4-fluorobenzyl)piperidin-1-yl]methyl)benzimidazol-5-yl)methanesulfonamide

Guidance literature:: With triethylamine; In dichloromethane;
DOI:10.1016/j.ejmech.2011.03.013

Reference yield:

: 1310689-10-1
2-[4-(4-fluorobenzyl)piperidin-1-yl]methyl-5-nitrobenzimidazole

: 1080622-46-3
N-(2-([4-(4-fluorobenzyl)piperidin-1-yl]methyl)benzimidazol-5-yl)methanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: palladium on carbon; hydrogen / methanol / 3.5 h / 20 °C / 1125.11 Torr

2: triethylamine / dichloromethane

With palladium on carbon; hydrogen; triethylamine; In methanol; dichloromethane;
DOI:10.1016/j.ejmech.2011.03.013

Reference yield:

: 92822-02-1
4-(4-fluorobenzyl)piperidine

: 1080622-46-3
N-(2-([4-(4-fluorobenzyl)piperidin-1-yl]methyl)benzimidazol-5-yl)methanesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: sodium carbonate / acetonitrile / 15 h / 70 °C

2: palladium on carbon; hydrogen / methanol / 3.5 h / 20 °C / 1125.11 Torr

3: triethylamine / dichloromethane

With palladium on carbon; hydrogen; sodium carbonate; triethylamine; In methanol; dichloromethane; acetonitrile;
DOI:10.1016/j.ejmech.2011.03.013