4-(4'-Fluorobenzyl)piperidine

Base Information

Chemical Name:4-(4'-Fluorobenzyl)piperidine
CAS No.:92822-02-1
Molecular Formula:C12H16FN
Molecular Weight:193.264
Hs Code.:2933399090
European Community (EC) Number:676-020-4
DSSTox Substance ID:DTXSID30395219
Nikkaji Number:J528.608E
Wikidata:Q27096023
Metabolomics Workbench ID:150294
ChEMBL ID:CHEMBL144527
Mol file:92822-02-1.mol

Synonyms:4-(4'-Fluorobenzyl)piperidine;92822-02-1;4-[(4-fluorophenyl)methyl]piperidine;4-(4-fluorobenzyl)piperidine;4-(4-fluoro-benzyl)-piperidine;CHEMBL144527;4-(P-FLUOROBENZYL)PIPERIDINE;MFCD03839825;PIPERIDINE, 4-[(4-FLUOROPHENYL)METHYL]-;piperidine 4;4-(4'-fluorobenzyl) piperidine;D0V4PB;SCHEMBL895063;4-(4-fluorobenzyl)-piperidine;BDBM15788;DTXSID30395219;JLAKCHGEEBPDQI-UHFFFAOYSA-N;HMS3604B15;4-(4-flourophenylmethyl)piperidine;4-(4-fluorophenyl)methyl-piperidine;4- (4-fluorophenyl)methyl-piperidine;AKOS005174548;AB16243;AC-6749;CS-W021997;DB07110;SS-4428;PD006096;4-(4-Fluorobenzyl)piperidine, AldrichCPR;FT-0647344;EN300-62671;Q-103077;Q27096023;F8889-8150;Z969111158

Suppliers and Price of 4-(4'-Fluorobenzyl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(4-Fluorobenzyl)piperidine
5g
$ 385.00

SynQuest Laboratories
4-[(4-Fluorophenyl)methyl]piperidine
1 g
$ 125.00

SynQuest Laboratories
4-[(4-Fluorophenyl)methyl]piperidine
250 mg
$ 50.00

Matrix Scientific
4-[(4-Fluorophenyl)methyl]piperidine >95%
5g
$ 387.00

Matrix Scientific
4-[(4-Fluorophenyl)methyl]piperidine >95%
1g
$ 166.00

Matrix Scientific
4-[(4-Fluorophenyl)methyl]piperidine >95%
500mg
$ 133.00

Crysdot
4-(4'-Fluorobenzyl)piperidine 95+%
1g
$ 230.00

Crysdot
4-(4'-Fluorobenzyl)piperidine 95+%
5g
$ 530.00

Chemenu
4-[(4-Fluorophenyl)methyl]piperidine 95%
25g
$ 674.00

Chemenu
4-[(4-Fluorophenyl)methyl]piperidine 95%
10g
$ 323.00

Total 37 raw suppliers

Chemical Property of 4-(4'-Fluorobenzyl)piperidine

Chemical Property:

Boiling Point:285 °C at 760 mmHg
PKA:10.57±0.10(Predicted)
Flash Point:126.2 °C
PSA：12.03000
Density:1.044g/cm³
LogP:2.69660
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:193.126677677
Heavy Atom Count:14
Complexity:158

Purity/Quality:

99%, ^*data from raw suppliers

4-(4-Fluorobenzyl)piperidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1CC2=CC=C(C=C2)F
Uses 4-(4-Fluorobenzyl)piperidine is a building block for the synthesis of many pharmaceutical compounds. 4-(4-Fluorobenzyl)piperidine has been used as a reactant for the synthesis of chemokine antagonists and non-peptidic β-secretase inhibitors

Technology Process of 4-(4'-Fluorobenzyl)piperidine

There total 20 articles about 4-(4'-Fluorobenzyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 276872-81-2
N-(t-butoxycarbonyl)-4-(4-fluorophenylmethyl)piperidine

: 92822-02-1
4-(4-fluorobenzyl)piperidine

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane;
DOI:10.1016/j.bmcl.2005.01.016

Reference yield:

: 193357-62-9
1-benzyl-4-(4-fluorobenzylidene)piperidine

: 92822-02-1
4-(4-fluorobenzyl)piperidine

Guidance literature:: With hydrogen; palladium dihydroxide; In ethanol; at 20 ℃; for 15h; under 2585.74 Torr;
DOI:10.1021/jm030483s

Reference yield:

: 25519-77-1
1-(4-(4-fluorobenzoyl)piperidin-1-yl)ethanone

: 25503-90-6
1-acetyl-piperidine-4-carboxylic acid

: 92822-02-1
4-(4-fluorobenzyl)piperidine

Guidance literature:: With sodium hydroxide; hydrazine hydrate; aluminium chloride; In thionyl chloride; fluorobenzene; diethyl ether; ethanol; di-isopropyl ether; water; ethylene glycol; Petroleum ether;