3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole

Base Information

• Chemical Name: 3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole
• CAS No.: 86538-57-0
• Molecular Formula: C₁₃H₁₁N₅O₂
• Molecular Weight: 269.263
• Mol file: 86538-57-0.mol

Synonyms:3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole

Chemical Property of 3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole

There total 3 articles about 3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

malonaldehydebis(dimethylacetal) (102-52-3) + N-(3-methyl-4-nitro-1-phenyl-1H-pyrazol-5-yl)hydrazine (86538-56-9) → 3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole (86538-57-0)

Guidance literature:

With hydrogenchloride; In ethanol; for 1h; Heating;

Reference yield:

5-chloro-3-methyl-4-nitro-1-phenyl-1H-pyrazole (13551-76-3) → 3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole (86538-57-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 68 percent / 85percent N₂H₄*H₂O / ethanol / 0.25 h / Heating

2: 60 percent / HCl / ethanol / 1 h / Heating

With hydrogenchloride; hydrazine hydrate; In ethanol;

Reference yield:

5-chloro-3-methyl-1-phenyl-1H-pyrazole (1131-17-5) → 3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole (86538-57-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 64 percent / acetic anhydride, fuming nitric acid / 4 h / 25 - 30 °C

2: 68 percent / 85percent N₂H₄*H₂O / ethanol / 0.25 h / Heating

3: 60 percent / HCl / ethanol / 1 h / Heating

With hydrogenchloride; nitric acid; acetic anhydride; hydrazine hydrate; In ethanol;

upstream raw materials:

malonaldehydebis(dimethylacetal)

N-(3-methyl-4-nitro-1-phenyl-1H-pyrazol-5-yl)hydrazine

5-chloro-3-methyl-1-phenyl-1H-pyrazole

5-chloro-3-methyl-4-nitro-1-phenyl-1H-pyrazole

Downstream raw materials:

4,4'-dinitro-1'-(2'',4''-dinitrophenyl)-3'-methyl-1,5'-bipyrazole

4,4'-dinitro-3'-methyl-1'-p-nitrophenyl-1,5'-bipyrazole

4,4'-dinitro-3'-methyl-1'-phenyl-1,5'-bipyrazole

3'-methyl-4'-nitro-1'-p-nitrophenyl-1,5'-bipyrazole