2-Bromo-6-chloroquinoline

Base Information

Chemical Name:2-Bromo-6-chloroquinoline
CAS No.:891842-50-5
Molecular Formula:C9H5BrClN
Molecular Weight:242.502
Hs Code.:2933499090
DSSTox Substance ID:DTXSID20591642
Wikidata:Q72453540
Mol file:891842-50-5.mol

Synonyms:2-bromo-6-chloroquinoline;891842-50-5;2-bromo-6-chloro-quinoline;SCHEMBL3304612;2-bromanyl-6-chloranyl-quinoline;DTXSID20591642;CZRQPBUNCHUQAN-UHFFFAOYSA-N;MFCD09261123;AKOS015904359;SB69453;CS-0225349;EN300-1234953;A843085

Suppliers and Price of 2-Bromo-6-chloroquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Bromo-6-chloroquinoline 95+%
1g
$ 515.00

Chemenu
2-Bromo-6-chloroquinoline 95%
1g
$ 482.00

Biosynth Carbosynth
2-Bromo-6-chloroquinoline
5 g
$ 1025.00

Biosynth Carbosynth
2-Bromo-6-chloroquinoline
2 g
$ 880.00

Biosynth Carbosynth
2-Bromo-6-chloroquinoline
1 g
$ 650.00

Biosynth Carbosynth
2-Bromo-6-chloroquinoline
500 mg
$ 450.00

Biosynth Carbosynth
2-Bromo-6-chloroquinoline
250 mg
$ 300.00

American Custom Chemicals Corporation
2-BROMO-6-CHLOROQUINOLINE 95.00%
5MG
$ 501.69

Alichem
2-Bromo-6-chloroquinoline
1g
$ 486.24

AK Scientific
2-Bromo-6-chloroquinoline
5g
$ 1433.00

Total 24 raw suppliers

Chemical Property of 2-Bromo-6-chloroquinoline

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.68
Boiling Point:328.087 °C at 760 mmHg
PKA:-0.31±0.43(Predicted)
Flash Point:152.222 °C
PSA：12.89000
Density:1.673 g/cm³
LogP:3.65070
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:240.92939
Heavy Atom Count:12
Complexity:165

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-6-chloroquinoline 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CC(=N2)Br)C=C1Cl

Technology Process of 2-Bromo-6-chloroquinoline

There total 3 articles about 2-Bromo-6-chloroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1810-67-9
6-chloroquinolin-2(1H)-oney

: 891842-50-5
2--bromo-6--chloroquinoline

Guidance literature:: With tetrabutylammomium bromide; phosphorus pentoxide; In xylene; at 220 ℃; for 0.277778h; microwave irradiation;

Reference yield: 72.0%

: 6563-10-6
6-chloroquinoline N-oxide

: 891842-50-5
2--bromo-6--chloroquinoline

Guidance literature:: With N,N-dimethyl-formamide; phosphorus(V) oxybromide; In dichloromethane; at 0 - 25 ℃; for 6h; regioselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2016.07.083

Reference yield:

: 612-57-7
6-chloroquinoline

: 891842-50-5
2--bromo-6--chloroquinoline

Guidance literature:: Multi-step reaction with 2 steps

1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 14 h / 0 - 20 °C

2.1: tetrabutylammomium bromide / dichloromethane / 0.17 h / 20 °C / Inert atmosphere; Molecular sieve

2.2: 20 °C / Inert atmosphere

With tetrabutylammomium bromide; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;
DOI:10.1021/ol3034675