2-amino-6-(2,2-difluoroethoxy)-4-(2-fluorophenyl)pyridine-3,5-dicarbonitrile

Base Information

Chemical Name:2-amino-6-(2,2-difluoroethoxy)-4-(2-fluorophenyl)pyridine-3,5-dicarbonitrile
CAS No.:391663-89-1
Molecular Formula:C₁₅H₉F₃N₄O
Molecular Weight:318.258
Hs Code.:

Synonyms:2-amino-6-(2,2-difluoroethoxy)-4-(2-fluorophenyl)pyridine-3,5-dicarbonitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-amino-6-(2,2-difluoroethoxy)-4-(2-fluorophenyl)pyridine-3,5-dicarbonitrile

Chemical Property:

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Technology Process of 2-amino-6-(2,2-difluoroethoxy)-4-(2-fluorophenyl)pyridine-3,5-dicarbonitrile

There total 2 articles about 2-amino-6-(2,2-difluoroethoxy)-4-(2-fluorophenyl)pyridine-3,5-dicarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 391663-87-9
C₁₃H₆ClFN₄

: 359-13-7
difluoroethanol

: 391663-89-1
2-amino-6-(2,2-difluoroethoxy)-4-(2-fluorophenyl)pyridine-3,5-dicarbonitrile

Guidance literature:: With sodium hydride; In DMF (N,N-dimethyl-formamide); at 0 - 20 ℃; for 3h;

Reference yield:

: 391663-89-1
2-amino-6-(2,2-difluoroethoxy)-4-(2-fluorophenyl)pyridine-3,5-dicarbonitrile

Guidance literature:

Reference yield:

: 391663-89-1
2-amino-6-(2,2-difluoroethoxy)-4-(2-fluorophenyl)pyridine-3,5-dicarbonitrile

: 38870-89-2
Methoxyacetyl chloride

: N-[3,5-dicyano-6-(2,2-difluoroethoxy)-4-(2-fluorophenyl)pyridin-2-yl]-2-methoxyacetamide

Guidance literature:: 2-amino-6-(2,2-difluoroethoxy)-4-(2-fluorophenyl)pyridine-3,5-dicarbonitrile; Methoxyacetyl chloride; With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃;

With sodium hydroxide; In tetrahydrofuran; water; at 0 ℃; for 2h;