(1R)-2-{2-[(1S)-1-(methylthio)ethyl]phenylselenenyl}-1-phenylethanol

Base Information

• Chemical Name: (1R)-2-{2-[(1S)-1-(methylthio)ethyl]phenylselenenyl}-1-phenylethanol
• CAS No.: 919081-20-2
• Molecular Formula: C₁₇H₂₀OSSe
• Molecular Weight: 351.371
• Mol file: 919081-20-2.mol

Synonyms:(1R)-2-{2-[(1S)-1-(methylthio)ethyl]phenylselenenyl}-1-phenylethanol

Chemical Property of (1R)-2-{2-[(1S)-1-(methylthio)ethyl]phenylselenenyl}-1-phenylethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R)-2-{2-[(1S)-1-(methylthio)ethyl]phenylselenenyl}-1-phenylethanol

There total 4 articles about (1R)-2-{2-[(1S)-1-(methylthio)ethyl]phenylselenenyl}-1-phenylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + C10H11F3O3S2Se (278790-75-3) → (1R)-2-{2-[(1S)-1-(methylthio)ethyl]phenylselenenyl}-1-phenylethanol (919081-20-2) + (S)-2-[2-((S)-1-Methylsulfanyl-ethyl)-phenylselanyl]-1-phenyl-ethanol

Guidance literature:

styrene; C₁₀H₁₁F₃O₃S₂Se; In methanol; dichloromethane; at -78 ℃;

With water; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/S0040-4039(00)00358-0

Reference yield:

2-{[(1S)-1-methylthio]-ethyl}phenylselenenyl bromide (919081-07-5) + styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) → (1R)-2-{2-[(1S)-1-(methylthio)ethyl]phenylselenenyl}-1-phenylethanol (919081-20-2) + (S)-2-[2-((S)-1-Methylsulfanyl-ethyl)-phenylselanyl]-1-phenyl-ethanol

Guidance literature:

With water; In acetonitrile; at -30 ℃; for 72h;

DOI:10.1002/ejoc.200600517

Reference yield:

2-{[(1S)-1-methylthio]-ethyl}phenylselenenyl chloride (919081-09-7) + styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) → (1R)-2-{2-[(1S)-1-(methylthio)ethyl]phenylselenenyl}-1-phenylethanol (919081-20-2) + (S)-2-[2-((S)-1-Methylsulfanyl-ethyl)-phenylselanyl]-1-phenyl-ethanol

Guidance literature:

With water; In acetonitrile; at -30 ℃; for 72h;

DOI:10.1002/ejoc.200600517

upstream raw materials:

styrene

C₁₀H₁₁F₃O₃S₂Se

2-{[(1S)-1-methylthio]-ethyl}phenylselenenyl bromide

2-{[(1S)-1-methylthio]-ethyl}phenylselenenyl chloride

Downstream raw materials:

(S)-1-phenylethanol