1-(5-(benzylcarbamoyl)-4-methylthiazol-2-yl)-2-oxo-1,2-dihydropyridin-4-yl trifluoromethanesulfonate

Base Information

Chemical Name:1-(5-(benzylcarbamoyl)-4-methylthiazol-2-yl)-2-oxo-1,2-dihydropyridin-4-yl trifluoromethanesulfonate
CAS No.:1105690-61-6
Molecular Formula:C₁₈H₁₄F₃N₃O₅S₂
Molecular Weight:473.453
Hs Code.:

Synonyms:1-(5-(benzylcarbamoyl)-4-methylthiazol-2-yl)-2-oxo-1,2-dihydropyridin-4-yl trifluoromethanesulfonate

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Chemical Property of 1-(5-(benzylcarbamoyl)-4-methylthiazol-2-yl)-2-oxo-1,2-dihydropyridin-4-yl trifluoromethanesulfonate

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Technology Process of 1-(5-(benzylcarbamoyl)-4-methylthiazol-2-yl)-2-oxo-1,2-dihydropyridin-4-yl trifluoromethanesulfonate

There total 1 articles about 1-(5-(benzylcarbamoyl)-4-methylthiazol-2-yl)-2-oxo-1,2-dihydropyridin-4-yl trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 358-23-6
trifluoromethylsulfonic anhydride

: 1105690-38-7
N-benzyl-2-(4-hydroxy-2-oxopyridin-1(2H)-yl)-4-methylthiazole-5-carboxamide

: 1105690-61-6
1-(5-(benzylcarbamoyl)-4-methylthiazol-2-yl)-2-oxo-1,2-dihydropyridin-4-yl trifluoromethanesulfonate

Guidance literature:: With pyridine; at -75 - -50 ℃; for 0.333333h;

Reference yield: 99.0%

: 1105690-61-6
1-(5-(benzylcarbamoyl)-4-methylthiazol-2-yl)-2-oxo-1,2-dihydropyridin-4-yl trifluoromethanesulfonate

: 1679-18-1
4-Chlorophenylboronic acid

: 1105690-60-5
N-benzyl-2-(4-(4-chlorophenyl)-2-oxopyridin-1(2H)-yl)-4-methylthiazole-5-carboxamide

Guidance literature:: With potassium phosphate; potassium bromide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; for 16h; Heating / reflux;

Reference yield: 54.0%

: 823-96-1
Trimethylboroxine

: 1105690-61-6
1-(5-(benzylcarbamoyl)-4-methylthiazol-2-yl)-2-oxo-1,2-dihydropyridin-4-yl trifluoromethanesulfonate

: 1105690-91-2
N-Benzyl-4-methyl-2-(4-methyl-2-oxopyridin-1(2H)-yl)thiazole-5-carboxamide

Guidance literature:: With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; ethyl acetate; for 18h; Heating / reflux;