Technology Process of methyl 2-(2,4-dimethylphenyl)-2-oxoethanoate
There total 3 articles about methyl 2-(2,4-dimethylphenyl)-2-oxoethanoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
2,2,6,6-tetramethyl-piperidine; 4-nitro-phenol; oxygen; potassium iodide;
for 11.5h;
Electrochemical reaction;
DOI:10.1002/chem.201302307
- Guidance literature:
-
monomethyl oxalyl chloride;
With
aluminum (III) chloride;
In
dichloromethane;
at 0 ℃;
for 0.5h;
Inert atmosphere;
m-xylene;
In
dichloromethane;
at 20 ℃;
for 1h;
With
hydrogenchloride;
In
dichloromethane; water;
Cooling with ice;
DOI:10.1021/ol101792a
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: selenium(IV) oxide; pyridine / 110 °C / Inert atmosphere
2.1: thionyl chloride / 13 h / 20 °C / Inert atmosphere; Molecular sieve; Cooling with ice
2.2: Inert atmosphere
With
pyridine; selenium(IV) oxide; thionyl chloride;
DOI:10.1016/j.tet.2016.07.046
