(S)-(+)-2-Oxo-4-phenyl-3-oxazolidineacetic acid

Base Information

Chemical Name:(S)-(+)-2-Oxo-4-phenyl-3-oxazolidineacetic acid
CAS No.:99333-54-7
Molecular Formula:C₁₁H₁₁NO₄
Molecular Weight:221.213
Hs Code.:
DSSTox Substance ID:DTXSID30357473
Nikkaji Number:J1.493.438C
Wikidata:Q72498927
Mol file:99333-54-7.mol

Synonyms:99333-54-7;(S)-(+)-2-Oxo-4-phenyl-3-oxazolidineacetic acid;(S)-2-(2-Oxo-4-phenyloxazolidin-3-yl)acetic acid;2-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]acetic acid;SCHEMBL42224;DTXSID30357473;PUKMRNJLFMISMT-SECBINFHSA-N;MFCD00192376;AKOS015915057;AC-8772;AS-40099;CS-0134779;(S)-4-phenyloxazolidin-2-one-3-ylacetic acid;(S) -4-phenyloxazolidin-2-one-3-ylacetic acid;2-(2-oxo-4-phenyl-oxazolidin-3-yl)acetic acid;A846005;(S)-2-(2-Oxo-4-phenyloxazolidin-3-yl)aceticacid;(S)-(+)-2-Oxo-4-phenyl-3-oxazolidineacetic acid, 98%

Suppliers and Price of (S)-(+)-2-Oxo-4-phenyl-3-oxazolidineacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(S)-(+)-2-Oxo-4-phenyl-3-oxazolidineacetic acid 98%
1g
$ 117.00

Sigma-Aldrich
(S)-(+)-2-Oxo-4-phenyl-3-oxazolidineacetic acid 98%
250mg
$ 33.10

Crysdot
(S)-2-(2-Oxo-4-phenyloxazolidin-3-yl)aceticacid 95+%
1g
$ 218.00

Chemenu
(S)-2-(2-oxo-4-phenyloxazolidin-3-yl)aceticacid 95%
1g
$ 206.00

American Custom Chemicals Corporation
(S)-(+)-2-OXO-4-PHENYL-3-OXAZOLIDINEACETIC ACID 95.00%
1G
$ 205.41

AK Scientific
(S)-2-(2-Oxo-4-phenyloxazolidin-3-yl)aceticacid
1g
$ 189.00

Total 43 raw suppliers

Chemical Property of (S)-(+)-2-Oxo-4-phenyl-3-oxazolidineacetic acid

Chemical Property:

Vapor Pressure:1.72E-11mmHg at 25°C
Melting Point:103-105 °C(lit.)
Refractive Index:1.579
Boiling Point:516.4 °C at 760 mmHg
PKA:4.00±0.10(Predicted)
Flash Point:266.1 °C
PSA：66.84000
Density:1.351 g/cm³
LogP:1.20240
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:221.06880783
Heavy Atom Count:16
Complexity:286

Purity/Quality:

99% ^*data from raw suppliers

(S)-(+)-2-Oxo-4-phenyl-3-oxazolidineacetic acid 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(N(C(=O)O1)CC(=O)O)C2=CC=CC=C2
Isomeric SMILES:C1[C@@H](N(C(=O)O1)CC(=O)O)C2=CC=CC=C2
Uses The chiral ketene derived from this product leads to chiral β-lactams via the Staudinger reaction. This strategy has been extended to prepare unnatural dipeptides.

Technology Process of (S)-(+)-2-Oxo-4-phenyl-3-oxazolidineacetic acid

There total 9 articles about (S)-(+)-2-Oxo-4-phenyl-3-oxazolidineacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 910322-90-6
(2-oxo-(4S)-phenyloxazolidin-3-yl) acetic acid benzyl ester

: 123882-32-6,136861-61-5,99333-54-7
2-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]acetic acid

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In ethyl acetate; at 23 ℃; for 3h;

Reference yield: 100.0%

: 99333-53-6
ethyl 2-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]acetate

: 123882-32-6,136861-61-5,99333-54-7
2-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]acetic acid

Guidance literature:: ethyl 2-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]acetate; With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 3h;

With hydrogenchloride; In tetrahydrofuran; water; ethyl acetate;
DOI:10.1021/acs.jmedchem.0c02094

Reference yield:

: 99395-88-7,7480-32-2
(S)-4-phenyl-2-oxazolidinone

: 105-36-2
ethyl bromoacetate

: 123882-32-6,136861-61-5,99333-54-7
2-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]acetic acid

Guidance literature:: (S)-4-phenyl-2-oxazolidinone; ethyl bromoacetate; With sodium hydride; In tetrahydrofuran; at -10 - 40 ℃; for 2h;

With sodium hydroxide; In tetrahydrofuran; water; for 2h;